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ADAMTS5

ADAM metallopeptidase with thrombospondin type 1 motif, 5

ADAMTS5 is a member of the ADAMTS (a disintegrin and metalloproteinase with thrombospondin motifs) protein family. Members of the family share several distinct protein modules, including a propeptide region, a metalloproteinase domain, a disintegrin-like domain, and a thrombospondin type 1 (TS) motif. Individual members of this family differ in the number of C-terminal TS motifs, and some have unique C-terminal domains. The enzyme encoded by this gene contains two C-terminal TS motifs and functions as aggrecanase to cleave aggrecan, a major proteoglycan of cartilage.

Gene Name: ADAM metallopeptidase with thrombospondin type 1 motif, 5
Family/Subfamily: Protease , Metallopeptidase M12B
Synonyms: ADAMTS5, Aggrecanase-2, ADAM-TS 11, ADAM-TS5, ADAMTS-11, ADAMTS11, ADAM-TS 5, ADAMTS-5, ADMP-2, ADMP2
Target Sequences: NM_007038 NP_008969.2 Q9UNA0

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Products
Antibodies (47)
Primary (47)
ADAMTS5 (47)
Human (47)
Mouse (12)
Rat (11)
Bat (1)
Bovine (1)
Dog (1)
Hamster (2)
Horse (1)
Monkey (4)
Pig (1)
IHC (10)
IHC-P (8)
WB (37)
ELISA (21)
IF (1)
IP (2)
Peptide-ELISA (1)
rabbit (45)
mouse (1)
goat (1)
Product Group
IHCPlus (5)
PathPlus Cancer (2)
IgG (21)
IgG2b (1)
monoclonal mc (1)
polyclonal pc (46)
APC (2)
APC Conjugated (4)
Azide-free (2)
Biotin Conjugated (5)
Cy3 Conjugated (2)
Cy7 Conjugated (2)
FITC Conjugated (5)
HRP Conjugated (5)
PE Conjugated (4)
Unconjugated (20)
aa267-622 (8)
aa485-622 (8)
aa26-54 (7)
aa331-360 (7)
Internal (3)
C-Terminus (1)
Metalloprotease Domain (1)
N-Terminus (1)
aa262-622 (1)
No (47)
ADAMTS5 Antibody - Breast, Carcinoma
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Cancer
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ADAMTS5 Rabbit anti-Human Polyclonal (Metalloprotease Domain) Antibody
Mouse, Dog, Rat, Hamster, Horse, Bat, Human, Monkey
IHC, IHC-P
Unconjugated
50 µg/$440
ADAMTS5 Antibody - Anti-ADAMTS5 antibody IHC of human placenta. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.
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Fast Shipping
ADAMTS5 Rabbit anti-Human Polyclonal (Internal) Antibody
Human, Monkey
IHC, IHC-P
Unconjugated
50 µg/$440
ADAMTS5 Antibody - Anti-ADAMTS5 antibody IHC of human placenta. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.
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Fast Shipping
ADAMTS5 Rabbit anti-Human Polyclonal (Internal) Antibody
Mouse, Bovine, Rat, Pig, Human, Monkey
IHC, IHC-P
Unconjugated
50 µg/$460
ADAMTS5 Antibody - Anti-ADAMTS5 antibody IHC of human placenta. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.
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Fast Shipping
ADAMTS5 Rabbit anti-Human Polyclonal (N-Terminus) Antibody
Human
IHC, IHC-P
Unconjugated
50 µg/$460
Select
ADAMTS5 Mouse anti-Human Monoclonal (aa262-622) Antibody
Human
ELISA, IP, WB
Unconjugated
100 µg/$896
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ADAMTS5 Goat anti-Human Polyclonal Antibody
Human
ELISA, IP, WB
Unconjugated
100 µg/$930
ADAMTS5 Antibody - ADAMTS5 Antibody western blot of K562 cell line lysates (35 ug/lane). The ADAMTS5 antibody detected the ADAMTS5 protein (arrow).
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ADAMTS5 Rabbit anti-Human Polyclonal (aa26-54) Antibody
Human
WB
Unconjugated
400 µl/$393
ADAMTS5 Antibody - Western blot analysis of extracts of various cells.
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ADAMTS5 Rabbit anti-Human Polyclonal Antibody
Mouse, Human
WB
Unconjugated
20 µl/$275; 100 µl/$389
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ADAMTS5 Rabbit anti-Human Polyclonal Antibody
Human
ELISA, IF, IHC, WB
Unconjugated
100 µg/$331
ADAMTS5 Antibody - Human Heart: Formalin-Fixed, Paraffin-Embedded (FFPE)
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ADAMTS5 Rabbit anti-Human Polyclonal (aa331-360) Antibody
Mouse, Human
IHC, IHC-P, WB
Unconjugated
200 µl/$460
ADAMTS5 Antibody - Anti-ADAMTS5 antibody IHC of human Lung, Non-Small Cell Carcinoma. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.
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Cancer
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ADAMTS5 Rabbit anti-Human Polyclonal (C-Terminus) Antibody
Human, Monkey
IHC, IHC-P
Unconjugated
50 µg/$460
ADAMTS5 Antibody - Anti-ADAMTS5 antibody IHC of human placenta. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.
Select
Fast Shipping
ADAMTS5 Rabbit anti-Human Polyclonal (Internal) Antibody
Hamster, Human
IHC, IHC-P
Unconjugated
50 µg/$460
ADAMTS5 Antibody - Immunohistochemistry Dilution at 1:400 and staining in paraffin-embedded human placenta tissue performed on a Leica BondTM system. After dewaxing and hydration, antigen retrieval was mediated by high pressure in a citrate buffer (pH 6.0). Section was blocked with 10% normal Goat serum 30min at RT. Then primary antibody (1% BSA) was incubated at 4°C overnight. The primary is detected by a biotinylated Secondary antibody and visualized using an HRP conjugated SP system.
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ADAMTS5 Rabbit anti-Human Polyclonal Antibody
Human
ELISA, IHC, IHC-P
Unconjugated
50 µg/$294; 100 µg/$360
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ADAMTS5 Rabbit anti-Human Polyclonal Antibody
Mouse, Rat, Human
IHC, Peptide-ELISA, WB
Unconjugated
100 µl/$379; 200 µl/$421
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ADAMTS5 Rabbit anti-Human Polyclonal (aa26-54) Antibody
Human
ELISA, WB
Unconjugated
200 µl/$734
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ADAMTS5 Rabbit anti-Human Polyclonal (aa26-54) (Biotin) Antibody
Human
ELISA, WB
Biotin Conjugated
200 µl/$952
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ADAMTS5 Rabbit anti-Human Polyclonal (aa26-54) (FITC) Antibody
Human
ELISA, WB
FITC Conjugated
200 µl/$952
Select
ADAMTS5 Rabbit anti-Human Polyclonal (aa26-54) (APC) Antibody
Human
ELISA, WB
APC Conjugated
200 µl/$952
Select
ADAMTS5 Rabbit anti-Human Polyclonal (aa26-54) (Azide-free) (HRP) Antibody
Human
ELISA, WB
HRP Conjugated, Azide-free
200 µl/$952
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ADAMTS5 Rabbit anti-Human Polyclonal (aa26-54) (PE) Antibody
Human
ELISA, WB
PE Conjugated
200 µl/$952
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ADAMTS5 Rabbit anti-Human Polyclonal (aa331-360) Antibody
Mouse, Human
ELISA, WB
Unconjugated
200 µl/$734
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ADAMTS5 Rabbit anti-Human Polyclonal (aa331-360) (Biotin) Antibody
Mouse, Human
ELISA, WB
Biotin Conjugated
200 µl/$952
Select
ADAMTS5 Rabbit anti-Human Polyclonal (aa331-360) (FITC) Antibody
Mouse, Human
ELISA, WB
FITC Conjugated
200 µl/$952
Select
ADAMTS5 Rabbit anti-Human Polyclonal Antibody
Mouse, Human
ELISA, WB
Unconjugated
100 µg/$357
ADAMTS5 Antibody
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ADAMTS5 Rabbit anti-Human Polyclonal Antibody
Human
ELISA, WB
Unconjugated
100 µl/$332
Viewing 1-25 of 47 product results


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PLEASE NOTE

For RESEARCH USE ONLY. Intended for use by laboratory professionals. Not intended for human diagnostic or therapeutic purposes.

The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).