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| Catalog Number | Size | Price |
|---|---|---|
| LS-A7768-50 | 50 µg (1 mg/ml) | $460 |
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PathPlus™ Polyclonal Rabbit anti‑Human ADAMTS5 Antibody (C‑Terminus, IHC) LS‑A7768
PathPlus™ Polyclonal Rabbit anti‑Human ADAMTS5 Antibody (C‑Terminus, IHC) LS‑A7768
Antibody:
ADAMTS5 Rabbit anti-Human Polyclonal (C-Terminus) Antibody
Application:
IHC, IHC-P
Reactivity:
Human, Monkey
Format:
Unconjugated, Unmodified
Overview
Antibody:
ADAMTS5 Rabbit anti-Human Polyclonal (C-Terminus) Antibody
Application:
IHC, IHC-P
Reactivity:
Human, Monkey
Format:
Unconjugated, Unmodified
Specifications
Description
ADAMTS5 is a member of the ADAMTS (a disintegrin and metalloproteinase with thrombospondin motifs) protein family. Members of the family share several distinct protein modules, including a propeptide region, a metalloproteinase domain, a disintegrin-like domain, and a thrombospondin type 1 (TS) motif. Individual members of this family differ in the number of C-terminal TS motifs, and some have unique C-terminal domains. The enzyme encoded by this gene contains two C-terminal TS motifs and functions as aggrecanase to cleave aggrecan, a major proteoglycan of cartilage.
References: The UniProt Consortium. Nucleic Acids Res. 47: D506-515 (2019); Nucleic Acids Res. 2016 Jan 4;44(D1):D733-45, PMID:26553804
Target
Human ADAMTS5
Synonyms
ADAMTS5 | Aggrecanase-2 | ADAM-TS 11 | ADAM-TS5 | ADAMTS-11 | ADAMTS11 | ADAM-TS 5 | ADAMTS-5 | ADMP-2 | ADMP2
Host
Rabbit
Reactivity
Human, Monkey
(tested or 100% immunogen sequence identity)
Predicted
Mouse, Rat, Bat, Dog, Hamster, Horse, Pig, Chicken (at least 90% immunogen sequence identity)
Clonality
Polyclonal
Conjugations
Unconjugated
Purification
Immunoaffinity purified
Modifications
Unmodified
Immunogen
Synthetic 16 amino acid peptide from C-Terminus of human ADAMTS5. Percent identity with other species by BLAST analysis: Human, Gorilla, Gibbon, Monkey, Marmoset, Panda, Lizard (100%); Mouse, Rat, Hamster, Elephant, Dog, Bat, Horse, Pig, Opossum, Turkey, Chicken (94%); Bovine (81%).
Epitope
C-Terminus
Specificity
Human ADAMTS5. BLAST analysis of the peptide immunogen showed no homology with other human proteins.
Applications
- IHC
- IHC - Paraffin (2 - 4 µg/ml)
|
Performing IHC? See our complete line of Immunohistochemistry Reagents including antigen retrieval solutions, blocking agents
ABC Detection Kits and polymers, biotinylated secondary antibodies, substrates and more.
|
Presentation
PBS, 0.1% Sodium Azide
Storage
Aliquot and store undiluted at -20°C or below for up to 1 year. Can be stored undiluted at 4°C for up to 1 month. Avoid freeze-thaw cycles.
Restrictions
For research use only. Intended for use by laboratory professionals.
About ADAMTS5
Validation
Breast, carcinoma
Breast, carcinoma
Lung, Non Small-Cell Carcinoma
Lung, Non Small-Cell Carcinoma
Ovary, carcinoma
Ovary, carcinoma
Anti-ADAMTS5 antibody IHC of human Lung, Non-Small Cell Carcinoma. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.
Anti-ADAMTS5 antibody IHC of human Lung, Non-Small Cell Carcinoma. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.
Breast, Carcinoma
Breast, Carcinoma
Anti-ADAMTS5 antibody IHC of human cartilage. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.
Anti-ADAMTS5 antibody IHC of human cartilage. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.
See More About...
LSBio Ratings
PathPlus™ ADAMTS5 Antibody (C-Terminus) for IHC LS-A7768 has an LSBio Rating of
Laboratory Validation Score (5)
Learn more about The LSBio Ratings Algorithm
Publications (0)
Customer Reviews (0)
Featured Products
Species:
Human, Monkey, Mouse, Rat, Bat, Dog, Hamster, Horse
Applications:
IHC, IHC - Paraffin
Species:
Human, Monkey
Applications:
IHC, IHC - Paraffin
Species:
Human, Mouse
Applications:
Western blot, ELISA
Species:
Human
Applications:
Western blot, Immunoprecipitation, ELISA
Request SDS/MSDS
To request an SDS/MSDS form for this product, please contact our Technical Support department at:
Technical.Support@LSBio.com
Requested From: United States
Date Requested: 11/22/2024
Date Requested: 11/22/2024
