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ACTN1

actinin, alpha 1

Alpha actinins belong to the spectrin gene superfamily which represents a diverse group of cytoskeletal proteins, including the alpha and beta spectrins and dystrophins. Alpha actinin is an actin-binding protein with multiple roles in different cell types. In nonmuscle cells, the cytoskeletal isoform is found along microfilament bundles and adherens-type junctions, where it is involved in binding actin to the membrane. In contrast, skeletal, cardiac, and smooth muscle isoforms are localized to the Z-disc and analogous dense bodies, where they help anchor the myofibrillar actin filaments. This gene encodes a nonmuscle, cytoskeletal, alpha actinin isoform and maps to the same site as the structurally similar erythroid beta spectrin gene. Three transcript variants encoding different isoforms have been found for this gene.

Gene Name: actinin, alpha 1
Synonyms: ACTN1, Alpha-actinin-1, Actinin 1 smooth muscle, Actinin, alpha 1, F-actin cross-linking protein, Non-muscle alpha-actinin-1, ASMA
Target Sequences: NM_001102 NP_001093.1 P12814

☰ Filters
Antibodies (58)
ELISA Kits (8)
Proteins (6)
Custom (4)
Over-Expression Lysate (2)
Primary (58)
Recombinant (4)
Sandwich (4)
ACTN1 (72)
Human (59)
Mouse (31)
Rat (24)
Bat (1)
Bovine (8)
Chicken (6)
Chimpanzee (6)
Dog (6)
Gibbon (6)
Guinea pig (7)
Hamster (4)
Horse (4)
Monkey (11)
Pig (4)
Rabbit (13)
Sheep (1)
Zebrafish (6)
IHC (24)
IHC-Fr (3)
IHC-P (6)
WB (56)
Flo (7)
ELISA (12)
ICC (8)
IF (5)
IP (2)
Peptide-ELISA (2)
rabbit (43)
mouse (14)
goat (1)
Product Group
IHCPlus (1)
IgG (28)
IgG1 (8)
IgG2a (2)
IgG2a,k (1)
IgG3,k (1)
monoclonal mc (14)
polyclonal pc (44)
1D4 (1)
3F1 (1)
AT1D10 (1)
CB11 (1)
OTI7A4 (2)
96-Well Strip Plate (8)
APC (1)
APC Conjugated (4)
Azide-free (1)
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Carrier-free (1)
Cy3 Conjugated (1)
Cy7 Conjugated (1)
FITC Conjugated (6)
HRP Conjugated (6)
PE Conjugated (4)
Unconjugated (30)
aa28-260 (8)
aa1-30 (7)
N-Terminus (5)
aa671-720 (4)
1-80 aa, N-terminal (1)
40-120 aa, N-terminal (1)
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Tyr193 (1)
aa596-609 (1)
aa650-893 (1)
No (72)
Cell Lysates (1)
Plasma (3)
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E. coli (1)
HEK 293 Cells (2)
Wheat Germ Extract (2)
Purified (1)
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ACTN1 Mouse anti-Human Monoclonal Antibody
Mouse, Rat, Human
IF, IHC, IHC-Fr, IHC-P, IP, WB
Unconjugated
100 µg/$564
ACTN1 Antibody - ICC/IF analysis of ACTN1 in Balb-3T3 cells. The cell was stained with ACTN1 antibody (1:100).The secondary antibody (green) was used Alexa Fluor 488. DAPI was stained the cell nucleus (blue).
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ACTN1 Mouse anti-Human Monoclonal (AT1D10) Antibody
Human
ELISA, Flo, ICC, WB
Unconjugated
50 µl/$303; 100 µl/$365
ACTN1 Antibody - Human Brain, Cortex: Formalin-Fixed, Paraffin-Embedded (FFPE)
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ACTN1 Rabbit anti-Human Polyclonal Antibody
Mouse, Human, Monkey
IHC, IHC-P, WB
Unconjugated
50 µl/$460
Select
ACTN1 Rabbit anti-Human Polyclonal (C-Terminus) Antibody
Mouse, Rat, Hamster, Human, Monkey
ICC, IF, WB
Unconjugated
100 µl/$688
ACTN1 Antibody - IHC of paraffin-embedded Human breast tissue using anti-ACTN1 mouse monoclonal antibody.
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ACTN1 Mouse anti-Human Monoclonal (OTI7A4) Antibody
Human
IF, IHC, IHC-P, WB
Unconjugated
100 µl/$434
ACTN1 Antibody - IHC of paraffin-embedded Human breast tissue using anti-ACTN1 mouse monoclonal antibody.
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ACTN1 Mouse anti-Human Monoclonal (aa650-893) (Carrier-free) (OTI7A4) Antibody
Human
IF, IHC, WB
Unconjugated, Carrier-free
100 µg/$511
ACTN1 Antibody - Formalin-fixed and paraffin-embedded human breast carcinoma with ACTN1 Antibody , which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. This data demonstrates the use of this antibody for immunohistochemistry; clinical relevance has not been evaluated.
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ACTN1 Rabbit anti-Human Polyclonal (aa1-30) Antibody
Human
Flo, IHC, IHC-P, WB
Unconjugated
400 µl/$393
Select
ACTN1 Mouse anti-Human Monoclonal Antibody
Rabbit, Mouse, Human
ICC, IHC, IHC-Fr, IP, WB
Unconjugated
200 µg/$907
Select
ACTN1 Mouse anti-Human Monoclonal (HRP) Antibody
Rabbit, Mouse, Human
ICC, IHC, WB
HRP Conjugated
100 µl/$1,119
Select
ACTN1 Mouse anti-Human Monoclonal (Biotin) Antibody
Rabbit, Mouse, Human
ICC, IHC, WB
Biotin Conjugated
100 µl/$1,119
Select
ACTN1 Mouse anti-Human Monoclonal (FITC) Antibody
Rabbit, Mouse, Human
ICC, IHC, WB
FITC Conjugated
100 µl/$1,119
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ACTN1 Mouse anti-Human Monoclonal (APC) Antibody
Rabbit, Mouse, Human
ICC, IHC, WB
APC Conjugated
100 µl/$1,119
Select
ACTN1 Mouse anti-Human Monoclonal (PE) Antibody
Rabbit, Mouse, Human
ICC, IHC, WB
PE Conjugated
100 µl/$1,119
Select
ACTN1 Rabbit anti-Human Polyclonal (aa1-30) (Biotin) Antibody
Human
ELISA, Flo, IHC, WB
Biotin Conjugated
200 µl/$952
Select
ACTN1 Rabbit anti-Human Polyclonal (aa1-30) (FITC) Antibody
Human
ELISA, Flo, IHC, WB
FITC Conjugated
200 µl/$952
Select
ACTN1 Rabbit anti-Human Polyclonal (aa1-30) (APC) Antibody
Human
ELISA, Flo, IHC, WB
APC Conjugated
200 µl/$952
Select
ACTN1 Rabbit anti-Human Polyclonal (aa1-30) (PE) Antibody
Human
ELISA, Flo, IHC, WB
PE Conjugated
200 µl/$952
Select
ACTN1 Rabbit anti-Human Polyclonal (aa1-30) (Azide-free) (HRP) Antibody
Human
ELISA, Flo, IHC, WB
HRP Conjugated, Azide-free
200 µl/$952
Select
ACTN1 Mouse anti-Chicken Monoclonal (CB11) Antibody
Chicken, Human
ELISA, IHC, IHC-Fr, WB
Unconjugated
100 µg/$890
ACTN1 ELISA Kit
Select
Sandwich
96-Well Strip Plate
Human
0.156 - 10 ng/ml
Colorimetric - 450nm (TMB)
Plasma, Serum
1 Plate/$669
ACTN1 Protein - Western validation with an anti-DDK antibody * L: Control HEK293 lysate R: Over-expression lysate
Select
293T Cells
Myc-DDK (Flag)
102.9 kDa
20 µg/$150
Select
ACTN1 Rabbit anti-Human Polyclonal Antibody
Human
ELISA, IHC, WB
Unconjugated
100 µg/$331
ACTN1 Antibody - Immunohistochemical analysis of ACTN1 staining in mouse kidney formalin fixed paraffin embedded tissue section. The section was pre-treated using heat mediated antigen retrieval with sodium citrate buffer (pH 6.0). The section was then incubated with the antibody at room temperature and detected using an HRP conjugated compact polymer system. DAB was used as the chromogen. The section was then counterstained with hematoxylin and mounted with DPX.
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ACTN1 Rabbit anti-Mouse Polyclonal Antibody
Mouse, Rat
IHC, IHC-P, WB
Unconjugated
100 µl/$321
ACTN1 Antibody - Western blot of Actinin-alpha1/2/3/4 antibody
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ACTN1 Rabbit anti-Human Polyclonal (40-120 aa, N-terminal) Antibody
Mouse, Rat, Human
ELISA, IHC, WB
Unconjugated
50 µg/$295; 100 µg/$335; 200 µg/$394
ACTN1 Antibody - Staining 293 cells by IF/ICC. The samples were fixed with PFA and permeabilized in 0.1% Triton X-100, then blocked in 10% serum for 45 min at 25°C. The primary antibody was diluted at 1:200 and incubated with the sample for 1 hour at 37°C. An Alexa Fluor 594 conjugated goat anti-rabbit IgG (H+L) antibody, diluted at 1/600, was used as secondary antibody.
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ACTN1 Rabbit anti-Human Polyclonal Antibody
Mouse, Rat, Human
IF, Peptide-ELISA, WB
Unconjugated
100 µl/$379; 200 µl/$421
Viewing 1-25 of 72 product results



If you do not find the reagent or information you require, please contact Customer.Support@LSBio.com to inquire about additional products in development.

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For RESEARCH USE ONLY. Intended for use by laboratory professionals. Not intended for human diagnostic or therapeutic purposes.

The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).