Orders Processing,
Shipping & Receiving,
Warehouse
2 Shaker Rd Suites
B001/B101
Shirley, MA 01464
Production Lab
Floor 6, Suite 620
20700 44th Avenue W
Lynnwood, WA 98036
Actins are highly conserved proteins that are involved in various types of cell motility, and maintenance of the cytoskeleton. In vertebrates, three main groups of actin isoforms, alpha, beta and gamma have been identified. The alpha actins are found in muscle tissues and are a major constituent of the contractile apparatus. The beta and gamma actins co-exist in most cell types as components of the cytoskeleton, and as mediators of internal cell motility. Actin, gamma 1, encoded by this gene, is a cytoplasmic actin found in non-muscle cells. Mutations in this gene are associated with DFNA20/26, a subtype of autosomal dominant non-syndromic sensorineural progressive hearing loss. Alternative splicing results in multiple transcript variants.
Gene Name: | actin, gamma 1 |
Synonyms: | ACTG1, ACTG, Actin, gamma 1, BRWS2, Cytoskeletal gamma-actin, DFNA20, Actin, cytoplasmic 2, Gamma-actin, DFNA26 |
Target Sequences: | NM_001614 NP_001605.1 P63261 |
If you do not find the reagent or information you require, please contact Customer.Support@LSBio.com to inquire about additional products in development.