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ACTA1 / Skeletal Muscle Actin
Actin, Alpha 1, Skeletal Muscle
Actin alpha 1 which is expressed in skeletal muscle is one of six different actin isoforms which have been identified. Actins are highly conserved proteins that are involved in cell motility, structure and integrity. Alpha actins are a major constituent of the contractile apparatus. The product encoded by this gene belongs to the actin family of proteins, which are highly conserved proteins that play a role in cell motility, structure and integrity. Alpha, beta and gamma actin isoforms have been identified, with alpha actins being a major constituent of the contractile apparatus, while beta and gamma actins are involved in the regulation of cell motility. This actin is an alpha actin that is found in skeletal muscle. Mutations in this gene cause nemaline myopathy type 3, congenital myopathy with excess of thin myofilaments, congenital myopathy with cores, and congenital myopathy with fiber-type disproportion, diseases that lead to muscle fiber defects.
| Gene Name: | Actin, Alpha 1, Skeletal Muscle |
| Synonyms: | ACTA1, ACTA, Actin, alpha skeletal muscle, Alpha-actin-1, CFTD, CFTD1, CFTDM, MPFD, NEM1, NEM2, ASMA, NEM3 |
| Target Sequences: | NM_001100 NP_001091.1 P68133 |
Publications (2)
1
How Different Stocking Densities Affect Growth and Stress Status of Acipenser baerii Early Stage Larvae. Lucia Aidos, Alessandra Cafiso, Valentina Serra, Mauro Vasconi, Daniela Bertotto, Chiara Bazzocchi, Giuseppe Radaelli, Alessia Di Giancamillo. Animals: an open access journal from MDPI. 2020 July;10: [Full Text Article]
[PubMed:32731504]
[PMC:PMC7460203]
Related Antibodies: LS-B4203.
2
TBX5 R264K acts as a modifier to develop dilated cardiomyopathy in mice independently of T-box pathway. Nariaki Miyao, Yukiko Hata, Hironori Izumi, Ryo Nagaoka, Yuko Oku, Ichiro Takasaki, Taisuke Ishikawa, Shinya Takarada, Mako Okabe, Hideyuki Nakaoka, Keijiro Ibuki, Sayaka Ozawa, Tomoyuki Yoshida, Hideyuki Hasegawa, Naomasa Makita, Naoki Nishida, Hisashi Mori, Fukiko Ichida, Keiichi Hirono. PloS one. 2020 Apr;15:e0227393. [Full Text Article]
[PubMed:32236096]
[PMC:PMC7112173]
Related Antibodies: LS-C413476.
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(3)
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Cancer
ACTA1 / Skeletal Muscle Actin Rabbit anti-Human Polyclonal Antibody
Fish, Zebrafish, Human
IHC, IHC-P, WB
Unconjugated
50 µl/$440
ACTA1 / Skeletal Muscle Actin Mouse anti-Human Monoclonal (3B3) Antibody
Rabbit, Goat, Rat, Pig, Human
ELISA, IHC, IHC-Fr, IHC-P, WB
Unconjugated
50 µg/$460
ACTA1 / Skeletal Muscle Actin Mouse anti-Human Monoclonal (aa3-12) (3B3) Antibody
Chicken, Bovine, Rabbit, Mouse, Goat, Guinea pig, Rat, Pig, Horse, Human, Monkey
ELISA, IHC, IHC-Fr, IHC-P, WB
Unconjugated
100 µg/$763
ACTA1 / Skeletal Muscle Actin Mouse anti-Human Monoclonal Antibody
Mouse, Rat, Human
IHC, IHC-P, IP, WB
Unconjugated
100 µl/$321
Cell-Based
96-Well Microplate
Mouse, Human, Rat
Colorimetric - 450nm (TMB)
Adherent Cell Cultures
1 Plate/$534
ACTA1 / Skeletal Muscle Actin Rabbit anti-Human Polyclonal (aa1-50) Antibody
Mouse, Rat, Human
IHC, Peptide-ELISA, WB
Unconjugated
50 µl/$334; 100 µl/$397
ACTA1 / Skeletal Muscle Actin Rabbit anti-Human Monoclonal Antibody
Human
ELISA, Flo, IF, IHC, IHC-P, WB
Unconjugated
50 µl/$316; 100 µl/$386
ACTA1 / Skeletal Muscle Actin Rabbit anti-Mouse Polyclonal Antibody
Mouse
ELISA, IHC, WB
Unconjugated
50 µg/$294; 100 µg/$360
ACTA1 / Skeletal Muscle Actin Rabbit anti-Human Polyclonal (aa277-308) Antibody
Mouse, Rat, Hamster, Human
IHC, IHC-P, WB
Unconjugated
10 µg/$318; 100 µg/$470
ACTA1 / Skeletal Muscle Actin Rabbit anti-Human Polyclonal (aa346-375) Antibody
Human
ELISA, Flo, IF, IHC, WB
Unconjugated
200 µl/$734
ACTA1 / Skeletal Muscle Actin Rabbit anti-Human Polyclonal (aa346-375) (Biotin) Antibody
Human
ELISA, Flo, ICC, IF, IHC, WB
Biotin Conjugated
200 µl/$952
ACTA1 / Skeletal Muscle Actin Rabbit anti-Human Polyclonal (aa346-375) (FITC) Antibody
Human
ELISA, Flo, ICC, IF, IHC, WB
FITC Conjugated
200 µl/$952
ACTA1 / Skeletal Muscle Actin Rabbit anti-Human Polyclonal (aa346-375) (PE) Antibody
Human
ELISA, Flo, ICC, IF, IHC, WB
PE Conjugated
200 µl/$952
ACTA1 / Skeletal Muscle Actin Rabbit anti-Human Polyclonal (aa346-375) (APC) Antibody
Human
ELISA, Flo, ICC, IF, IHC, WB
APC Conjugated
200 µl/$952
ACTA1 / Skeletal Muscle Actin Rabbit anti-Human Polyclonal (aa346-375) (Azide-free) (HRP) Antibody
Human
ELISA, Flo, ICC, IF, IHC, WB
HRP Conjugated, Azide-free
200 µl/$952
ACTA1 / Skeletal Muscle Actin Mouse anti-Human Monoclonal Antibody
Human
Flo, IHC, IHC-P, WB
Unconjugated
400 µl/$393
ACTA1 / Skeletal Muscle Actin Rabbit anti-Human Polyclonal Antibody
Mouse, Rat, Human
IF, IHC, IP, Peptide-ELISA, WB
Unconjugated
100 µl/$379; 200 µl/$421
ACTA1 / Skeletal Muscle Actin Mouse anti-Human Monoclonal (Biotin) (337CT30.10.1) Antibody
Human
ELISA, Flo, IHC, WB
Biotin Conjugated
200 µl/$952
ACTA1 / Skeletal Muscle Actin Mouse anti-Human Monoclonal (FITC) (337CT30.10.1) Antibody
Human
ELISA, Flo, IHC, WB
FITC Conjugated
200 µl/$952
ACTA1 / Skeletal Muscle Actin Mouse anti-Human Monoclonal (APC) (337CT30.10.1) Antibody
Human
ELISA, Flo, IHC, WB
APC Conjugated
200 µl/$952
ACTA1 / Skeletal Muscle Actin Mouse anti-Human Monoclonal (PE) (337CT30.10.1) Antibody
Human
ELISA, Flo, IHC, WB
PE Conjugated
200 µl/$952
ACTA1 / Skeletal Muscle Actin Mouse anti-Human Monoclonal (Azide-free) (HRP) (337CT30.10.1) Antibody
Human
ELISA, Flo, IHC, WB
HRP Conjugated, Azide-free
200 µl/$952
ACTA1 / Skeletal Muscle Actin Rabbit anti-Human Polyclonal (N-Terminus) Antibody
Chicken, Bovine, Rabbit, Mouse, Rat, Pig, Human
IHC, IHC-P, IP, WB
Unconjugated
100 µl/$299
ACTA1 / Skeletal Muscle Actin Mouse anti-Human Monoclonal (4A6) Antibody
Mouse, Rat, Human
IF, IHC-P, IP, WB
Unconjugated
20 µl/$254; 60 µl/$296; 120 µl/$355; 200 µl/$450
Sandwich
96-Well Strip Plate
Human
0.313 - 20 ng/ml
Colorimetric - 450nm (TMB)
Plasma, Serum, Tissue Homogenates
1 Plate/$579
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