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ABCC2 / MRP2
ATP-binding cassette, sub-family C (CFTR/MRP), member 2
ABCC2 is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intra-cellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). This protein is a member of the MRP subfamily which is involved in multi-drug resistance. This protein is expressed in the canalicular (apical) part of the hepatocyte and functions in biliary transport. Substrates include anticancer drugs such as vinblastine; therefore, this protein appears to contribute to drug resistance in mammalian cells. Several different mutations in this gene have been observed in patients with Dubin-Johnson syndrome (DJS), an autosomal recessive disorder characterized by conjugated hyperbilirubinemia.
| Gene Name: | ATP-binding cassette, sub-family C (CFTR/MRP), member 2 |
| Family/Subfamily: | Transporter , ATP-binding cassette - ABCC/MRP |
| Synonyms: | ABCC2, ABC30, CMOAT1, CMOAT, DJS, Multidrug resistance protein 2, MRP2, CMRP |
| Target Sequences: | NM_000392 NP_000383.1 Q92887 |
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Antibodies
(47)
Type
Primary
(47)
Target
ABCC2 / MRP2
(47)
Reactivity
Human
(45)
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(9)
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(6)
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(3)
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(3)
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(3)
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(3)
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IHC
(20)
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(9)
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(13)
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(40)
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(7)
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(7)
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(9)
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(3)
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(2)
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(3)
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rabbit
(33)
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(12)
rabbit-new zealand white
(2)
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(4)
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(17)
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(4)
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(1)
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(4)
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(3)
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monoclonal mc
(12)
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(35)
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(1)
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(1)
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(2)
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(2)
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(2)
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(2)
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(1)
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(1)
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(3)
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(1)
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(4)
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(1)
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(1)
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(3)
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(3)
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(1)
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(34)
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(8)
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(4)
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(2)
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(2)
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(1)
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(1)
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(1)
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(1)
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(1)
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(1)
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(1)
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(1)
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(1)
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(1)
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(1)
Publications
No
(47)
ABCC2 / MRP2 Rabbit anti-Human Polyclonal (Internal) Antibody
Mouse, Rat, Human
IHC, IHC-P, WB
Unconjugated
50 µl/$460
ABCC2 / MRP2 Mouse anti-Human Monoclonal (Concentrated) (M2III-6) Antibody
Human
ICC, IHC, IHC-Fr, IHC-P, WB
Unconjugated, Concentrated
1 ml/$509
ABCC2 / MRP2 Rabbit anti-Human Polyclonal Antibody
Human
IHC, IHC-P, WB
Unconjugated
100 µg/$332
ABCC2 / MRP2 Rabbit anti-Mouse Polyclonal (aa651-700) Antibody
Mouse
WB
Unconjugated
100 µl/$424
ABCC2 / MRP2 Rabbit anti-Human Polyclonal Antibody
Human
IF, IP, WB
Unconjugated
100 µl/$688
ABCC2 / MRP2 Rabbit anti-Mouse Polyclonal (C-Terminus) Antibody
Mouse
ELISA, WB
Unconjugated
0.1 mg/$379
ABCC2 / MRP2 Rabbit anti-Human Polyclonal Antibody
Human
ELISA, IF
Unconjugated
50 µg/$294; 100 µg/$360
ABCC2 / MRP2 Mouse anti-Human Monoclonal (Concentrated) (M2I-4) Antibody
Human
Flo, ICC, IHC, IHC-Fr, WB
Unconjugated, Concentrated
1 ml/$522
ABCC2 / MRP2 Rabbit anti-Human Polyclonal (aa991-1040) Antibody
Human
IHC, IHC-P, Peptide-ELISA, WB
Unconjugated
100 µl/$515
ABCC2 / MRP2 Rabbit anti-Human Polyclonal (aa977-1026) Antibody
Human
IHC, IHC-P, Peptide-ELISA, WB
Unconjugated
50 µl/$440
ABCC2 / MRP2 Mouse anti-Rat Monoclonal (aa1339-1541) Antibody
Rat, Human
ICC, IHC, IHC-Fr, WB
Unconjugated
125 µg/$907
ABCC2 / MRP2 Rabbit anti-Human Polyclonal (aa825-875) Antibody
Human
IHC, IHC-P, IP
Unconjugated
50 µl/$460
ABCC2 / MRP2 Mouse anti-Human Monoclonal (aa215-310) (M21-4) Antibody
Human
Flo, ICC, IHC, IHC-Fr, IHC-P, WB
Unconjugated
1 ml/$836
ABCC2 / MRP2 Mouse anti-Human Monoclonal (aa860-950) (M2II-12) Antibody
Human
Flo, ICC, IHC, IHC-Fr, IHC-P, WB
Unconjugated
1 ml/$836
ABCC2 / MRP2 Mouse anti-Human Monoclonal (C-Terminus) (M2III-6) Antibody
Human
Flo, ICC, IHC, IHC-Fr, IHC-P, WB
Unconjugated
1 ml/$754
ABCC2 / MRP2 Mouse anti-Human Monoclonal (M2III-5) Antibody
Human
Flo, ICC, IHC, IHC-Fr, IHC-P, WB
Unconjugated
1 ml/$836
ABCC2 / MRP2 Mouse anti-Human Monoclonal (Concentrated) (M2III-5) Antibody
Human
Flo, ICC, IHC, IHC-Fr, IHC-P, WB
Unconjugated, Concentrated
1 ml/$522
ABCC2 / MRP2 Mouse anti-Human Monoclonal (Concentrated) (M2II-12) Antibody
Human
Flo, ICC, IHC, IHC-Fr, WB
Unconjugated, Concentrated
1 ml/$522
ABCC2 / MRP2 Rabbit anti-Human Polyclonal Antibody
Mouse, Rat, Human
IF, Peptide-ELISA, WB
Unconjugated
100 µl/$379; 200 µl/$421
ABCC2 / MRP2 Rabbit anti-Human Polyclonal Antibody
Human
ELISA, IHC, WB
Unconjugated
100 µg/$341
ABCC2 / MRP2 Mouse anti-Human Monoclonal (aa1256-1545) (OTI5C3) Antibody
Rat, Human
IHC, WB
Unconjugated
100 µl/$434
ABCC2 / MRP2 Mouse anti-Human Monoclonal (aa1256-1545) (Carrier-free) (OTI5C3) Antibody
Rat, Human
IHC, WB
Unconjugated, Carrier-free
100 µg/$511
ABCC2 / MRP2 Rabbit anti-Human Polyclonal Antibody
Mouse, Human
IHC-P, WB
Unconjugated
100 µg/$575
ABCC2 / MRP2 Rabbit anti-Human Polyclonal Antibody
Human
ELISA, IHC
Unconjugated
20 µl/$254; 60 µl/$296; 120 µl/$355; 200 µl/$450
ABCC2 / MRP2 Mouse anti-Human Monoclonal (1C5) Antibody
Human
ELISA, WB
Unconjugated
100 µg/$423
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of 47
product results
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