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| Catalog Number | Size | Price |
|---|---|---|
| LS-G137119-20 | 20 µg | $364 |
| LS-G137119-100 | 100 µg | $500 |
| LS-G137119-1 | 1 mg | $1,679 |
Rat SORT1 / Sortilin Protein (Recombinant 6His, N-terminus) - LS-G137119
Rat SORT1 / Sortilin Protein (Recombinant 6His, N-terminus) - LS-G137119
Description:
SORT1 / Sortilin Protein LS-G137119 is a Recombinant Rat SORT1 / Sortilin produced in E. coli 610-754aa with 6His, N-terminus tag(s). For Research Use Only
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(800) 227-6666
(800) 227-6666For Research Use Only
Overview
Description:
SORT1 / Sortilin Protein LS-G137119 is a Recombinant Rat SORT1 / Sortilin produced in E. coli 610-754aa with 6His, N-terminus tag(s). For Research Use Only
Specifications
Type
Recombinant Protein
Target
SORT1 / Sortilin
Synonyms
SORT1 | 100 kDa NT receptor | gp95 | LDLCQ6 | Glycoprotein 95 | NTR3 | Sortilin 1 | Sortilin | Neurotensin receptor 3
Species
Rat
Modifications
Unmodified
Conjugations
Unconjugated
Tag
6His, N-terminus
Region
610-754aa
Predicted Molecular Weight
20.5 kDa
AA Sequence
CEENDYTTWLAHSTDPGDYKDGCILGYKEQFLRLRKSSVCQNGRDYVVAKQPSICPCSLEDFLCDFGYFRPENASECVEQPELKGHELEFCLYGKEEHLTTNGYRKIPGDRCQGGMNPAREVKDLKKKCTSNFLNPKKQNSKSSS
Expression System
E. coli
Source Species
E. coli
Purification
Greater than 90% by SDS-PAGE
Usage Summary
Functions as a sorting receptor in the Golgi compartment and as a clearance receptor on the cell surface. Required for protein transport from the Golgi apparatus to the lysosomes by a pathway that is independent of the mannose-6-phosphate receptor (M6PR). Also required for protein transport from the Golgi apparatus to the endosomes. Promotes neuronal apoptosis by mediating endocytosis of the proapoptotic precursor forms of BDNF (proBDNF) and NGFB (proNGFB). Also acts as a receptor for neurotensin. May promote mineralization of the extracellular matrix during osteogenic differentiation by scavenging extracellular LPL. Probably required in adipocytes for the formation of specialized storage vesicles containing the glucose transporter SLC2A4/GLUT4 (GLUT4 storage vesicles, or GSVs). These vesicles provide a stable pool of SLC2A4 and confer increased responsiveness to insulin. May also mediate transport from the endoplasmic reticulum to the Golgi.
Bio-Activity
Not Tested
Endotoxin
Not Tested
Presentation
Lyophilized from Tris, 50% Glycerol
Storage
Store at -80°C for up to 1 year. Avoid freeze-thaw cycles.
Restrictions
For research use only. Intended for use by laboratory professionals.
About SORT1 / Sortilin
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Images
Sodium Dodecyl Sulfate - Polyacrylamide Gel Electrophoresis
(Tris-Glycine gel) Discontinuous SDS-PAGE (reduced) with 5% enrichment gel and 15% separation gel.
Sodium Dodecyl Sulfate - Polyacrylamide Gel Electrophoresis
(Tris-Glycine gel) Discontinuous SDS-PAGE (reduced) with 5% enrichment gel and 15% separation gel.
Sodium Dodecyl Sulfate - Polyacrylamide Gel Electrophoresis
(Tris-Glycine gel) Discontinuous SDS-PAGE (reduced) with 5% enrichment gel and 15% separation gel.
Sodium Dodecyl Sulfate - Polyacrylamide Gel Electrophoresis
(Tris-Glycine gel) Discontinuous SDS-PAGE (reduced) with 5% enrichment gel and 15% separation gel.
Popular SORT1 / Sortilin Proteins
Source:
E. coli
Tag:
His-GST
Request SDS/MSDS
To request an SDS/MSDS form for this product, please contact our Technical Support department at:
Technical.Support@LSBio.com
Requested From: United States
Date Requested: 11/25/2024
Date Requested: 11/25/2024
