Target
TNFRSF9 / 4-1BB / CD137
Synonyms
TNFRSF9 | 4-1BB ligand receptor | 4-1BB | CD137 antigen | CD137 | Homolog of mouse 4-1BB | ILA | Receptor protein 4-1BB | T cell antigen ILA | T-cell antigen 4-1BB homolog | T-cell antigen ILA | CDw137
Conjugations
Unconjugated
Predicted Molecular Weight
17.7 kDa
AA Sequence
ERTRSLQDPCSNCPAGTFCDNNRNQICSPCPPNSFSSAGGQRTCDICRQCKGVFRTRKECSSTSNAECDCTPGFHCLGAGCSMCEQDCKQGQELTKKGCKDCCFGTFNDQKRGICRPWTNCSLDGKSVLVNGTKERDVVCGPSPADLSPGASSVTPPAPAREPGHS
Purification
Greater than 97% by SDS-PAGE and HPLC
Usage Summary
A single non-glycosylated polypeptide chain containing 166 amino acids.
Bio-Activity
Fully biologically active when compared to standard. The biological activity is determined by its inhibitory effect of IL-8 production using human peripheral blood mononuclear cells. About 90 % of inibition was seen using a concentration of 1 µg for both 4-1BB Ligand and 4-1BB Receptor.
Endotoxin
Less than 1 EU/µg (determined by LAL method).
Presentation
Lyophilized from a 0.2 um filtered concentrated solution in 10 mM PB, pH 8.0, 150 mM NaCl
Reconstitution
Briefly centrifuge prior to opening. Reconstitute in sterile distilled water or aqueous buffer containing 0.1 % BSA to a concentration of 0.1-1.0 mg/ml.
Storage
Store lyophilized at 2°C to 8°C for short term storage. Store lyophilized at -20°C for long term storage. Store reconstituted at 2°C to 8°C for up to 1 week. Aliquot and store reconstituted at -20°C to -70°C. Avoid repeated freeze/thaw cycles.
Restrictions
For research use only. Intended for use by laboratory professionals.
Guarantee
This protein carries the LSBio 100% Guarantee.
LSBio Guarantee
About TNFRSF9 / 4-1BB / CD137