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Corporate Headquarters
Vector Laboratories, Inc.
6737 Mowry Ave
Newark, CA 94560
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Customer Service: (800) 227-6666 / (650) 697-3600
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Registration enables users to use special features of this website, such as past
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order histories, retained contact details for faster checkout, review submissions, and special promotions.
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order histories, retained contact details for faster checkout, review submissions, and special promotions.
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TNFRSF9 / 4-1BB / CD137
tumor necrosis factor receptor superfamily, member 9
TNFRSF9 / 4-1BB / CD137 is a member of the TNF-receptor superfamily. This receptor contributes to the clonal expansion, survival, and development of T cells. It can also induce proliferation in peripheral monocytes, enhance T cell apoptosis induced by TCR/CD3 triggered activation, and regulate CD28 co-stimulation to promote Th1 cell responses. The expression of this receptor is induced by lymphocyte activation. TRAF adaptor proteins have been shown to bind to this receptor and transduce the signals leading to activation of NF-kappaB.
| Gene Name: | tumor necrosis factor receptor superfamily, member 9 |
| Family/Subfamily: | TNF Receptor , not assigned-TNF Receptor |
| Synonyms: | TNFRSF9, 4-1BB ligand receptor, 4-1BB, CD137 antigen, CD137, Homolog of mouse 4-1BB, ILA, Receptor protein 4-1BB, T cell antigen ILA, T-cell antigen 4-1BB homolog, T-cell antigen ILA, CDw137 |
| Target Sequences: | NM_001561 NP_001552.2 Q07011 |
Publications (2)
1
Progression of benign prostatic hyperplasia is associated with pro-inflammatory mediators and chronic activation of prostate-infiltrating lymphocytes. Norström MM, Rådestad E, Sundberg B, Mattsson J, Henningsohn L, Levitsky V, Uhlin M. Oncotarget. 2016 7:23581-93. (Flo, ELISA; Human)
[Full Text Article]
[PubMed:26993768]
[PMC:PMC5029649]
2
CD137 (4-1BB) Engagement Fine-Tunes Synergistic IL-15- and IL-21-Driven NK Cell Proliferation. Laurent Vidard, Christine Dureuil, Jérémy Baudhuin, Lionel Vescovi, Laurence Durand, Véronique Sierra, Eric Parmantier. Journal of immunology (Baltimore, Md. : 1950). 2019 August;203:676-685. [Full Text Article]
[PubMed:31201235]
☰ Filters
Products
Proteins
(33)
Type
Recombinant
(33)
Target
TNFRSF9 / 4-1BB / CD137
(33)
Publications
No
(33)
Tag
6His, C-terminus
(4)
DDK (Flag)-His, C-terminus
(1)
Fc
(1)
Fc, C-terminus
(6)
Fc/6His,C-terminus
(1)
Fc-6His, C-terminus
(2)
GST
(1)
GST, N-terminus
(2)
His
(3)
His, N-Terminal
(1)
His,C-terminus
(1)
Human IgG1 Fc
(3)
Human IgG1 Fc, C-terminus
(1)
mFc, C-terminus
(1)
Mouse IgG2a Fc, N-terminus
(1)
Species
Crab-eating macaque
(2)
Cynomolgus
(1)
Human
(26)
Mouse
(4)
Source
CHO Cells
(2)
E. coli
(8)
HEK 293 Cells
(4)
Human Cells
(5)
Mammalian Cells
(11)
Wheat Germ Extract
(3)
Purification
Purified
(11)
Low Endotoxin Level
Low endotoxin level
(25)
Biologically Active
Biologically active
(10)
Mammalian Cells
6His, C-terminus
Less than 0.1 ng/mL (Less than 1 EU/µg) (determined by LAL method).
10 µg/$266; 50 µg/$339; 500 µg/$1,010; 1 mg/$1,329
E. coli
None
Biologically active
17.7 kDa
5 µg/$282; 100 µg/$957; 500 µg/$1,747
CHO Cells
Human IgG1 Fc
Biologically active
Less than 0.06 EU/µg protein (determined by LAL method).
100 µg/$463
E. coli
His, N-Terminal
16kDa
10 µg/$283; 50 µg/$452; 200 µg/$902; 100 µg/$722; 1 mg/$2,016; 500 µg/$1,553; 5 mg/$3,151; 2 mg/$2,204
HEK 293 Cells
Human IgG1 Fc
Less than 0.1 EU/µg protein (determined by LAL method).
~50kDa (SDS-PAGE)
50 µg/$414
E. coli
None
Biologically active
Less than 0.1 ng/µg of protein (less than 1EU/µg).
17.7 kDa
5 µg/$268; 20 µg/$349
Wheat Germ Extract
GST
54.3 kDa
10 µg/$479; 25 µg/$670
Human Cells
Fc-6His, C-terminus
Less than 1.0 EU/µg protein (determined by LAL method).
44kD
10 µg/$284; 50 µg/$365; 500 µg/$1,408; 1 mg/$2,059
Human Cells
Fc, C-terminus
Less than 1.0 EU/µg protein (determined by LAL method).
44.7kD
10 µg/$277; 50 µg/$395; 500 µg/$1,203; 1 mg/$1,627
Wheat Germ Extract
GST, N-terminus
10 µg/$479; 25 µg/$670
Wheat Germ Extract
GST, N-terminus
10 µg/$479; 25 µg/$670
Human Cells
6His, C-terminus
Less than 1.0 EU/µg protein (determined by LAL method).
18.1kD
10 µg/$255; 50 µg/$343; 500 µg/$1,329; 1 mg/$1,863
Human Cells
Fc, C-terminus
Less than 1.0 EU/µg protein (determined by LAL method).
44.2kD
10 µg/$255; 50 µg/$343; 500 µg/$1,329; 1 mg/$1,863
HEK 293 Cells
DDK (Flag)-His, C-terminus
20 kDa
20 µg/$1,107
CHO Cells
Human IgG1 Fc, C-terminus
Biologically active
Less than 0.2 EU/µg protein (determined by LAL method).
55-60 kDa
1 mg/$1,475; 50 µg/$313
E. coli
None
Biologically active
Less than 1 EU/µg (determined by LAL method).
17.7 kDa
1 mg/$2,653; 20 µg/$364; 5 µg/$278
HEK 293 Cells
Mouse IgG2a Fc, N-terminus
Biologically active
Less than 5.0 EU/mg protein (determined by LAL method).
~55 kDa (SDS-PAGE)
100 µg/$463
Mammalian Cells
Fc-6His, C-terminus
Biologically active
Less than 1.0 EU/µg protein (determined by LAL method).
44 kDa
50 µg/$414; 10 µg/$308; 1 mg/$2,708; 500 µg/$1,701
Mammalian Cells
6His, C-terminus
Biologically active
Less than 1.0 EU/µg protein (determined by LAL method).
18.1 kDa
50 µg/$385; 10 µg/$269; 1 mg/$2,451; 500 µg/$1,612
Mammalian Cells
Fc, C-terminus
Biologically active
Less than 1.0 EU/µg protein (determined by LAL method).
44.2 kDa
50 µg/$385; 10 µg/$269; 1 mg/$2,451; 500 µg/$1,612
Mammalian Cells
Fc, C-terminus
Less than 1.0 EU/µg protein (determined by LAL method).
44.7 kDa
10 µg/$365; 50 µg/$479
Mammalian Cells
Fc/6His,C-terminus
Less than 1.0 EU/µg protein (determined by LAL method).
44.0 kDa
10 µg/$284; 50 µg/$361
Mammalian Cells
Fc, C-terminus
Less than 1.0 EU/µg protein (determined by LAL method).
44.4 kDa
10 µg/$266; 50 µg/$335
Mammalian Cells
6His, C-terminus
Less than 1.0 EU/µg protein (determined by LAL method).
18.1 kDa
10 µg/$255; 50 µg/$339
Mammalian Cells
Fc, C-terminus
Less than 1.0 EU/µg protein (determined by LAL method).
44.2 kDa
10 µg/$255; 50 µg/$339
Viewing 1-25
of 33
product results
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