Target
TNFRSF14 / CD270 / HVEM
Synonyms
TNFRSF14 | CD270 | CD270 antigen | CD40-like protein | Herpesvirus entry mediator | Herpesvirus entry mediator A | HVEM | LIGHTR | Herpes virus entry mediator A | TR2 | ATAR | HVEA
Modifications
Carrier-free
Conjugations
Unconjugated
Predicted Molecular Weight
The 376 amino acid recombinant protein consists of an N-terminal domain corresponding to the extracellular domain of HVEM and C-terminal portion corresponding to amino acid 102 to 330 of human IgG1. The protein has a predicted molecular mass of approximat
Expression System
Insect Cells
Purification
Greater than 98% by SDS-PAGE
Usage Summary
Reconstitute in water to a concentration of 0.1-1.0 mg/ml. Do not vortex. It is recommended to further dilute in a buffer containing a carrier protein such as 0.1% BSA.
Bio-Activity
Human HVEM-Fc is able to neutralize 0.25 ng/ml of human TNF-β induced cytotoxicity on murine L929 cells. The ED50 is 1.3 - 1.9 µg/ml, corresponding to a specific activity of 5.26 x 10^2 - 7.69 x 10^2 units/mg.
Endotoxin
Less than 0.1 ng/µg of protein.
Storage
Store unopened at -20°C to -70°C. Store diluted at -20°C to -80°C. Avoid freeze/thaw cycles. For maximum results, quick spin vial prior to opening.
Restrictions
For research use only. Intended for use by laboratory professionals.
Guarantee
This protein carries the LSBio 100% Guarantee.
LSBio Guarantee
About TNFRSF14 / CD270 / HVEM