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| Catalog Number | Size | Price |
|---|---|---|
| LS-G136825-10 | 10 µg | $235 |
| LS-G136825-50 | 50 µg | $255 |
| LS-G136825-500 | 500 µg | $346 |
| LS-G136825-1 | 1 mg | $404 |
Human IGF1 Protein (Recombinant) (Full Length) - LS-G136825
Human IGF1 Protein (Recombinant) (Full Length) - LS-G136825
Description:
IGF1 Protein LS-G136825 is a Recombinant Human IGF1 produced in E. coli 49-118aa. It is biologically active and is low in endotoxin; Less than 0.5 EU/µg protein (determined by LAL method). For Research Use Only
Toll Free North America
206-374-1102
206-374-1102For Research Use Only
Overview
Description:
IGF1 Protein LS-G136825 is a Recombinant Human IGF1 produced in E. coli 49-118aa. It is biologically active and is low in endotoxin; Less than 0.5 EU/µg protein (determined by LAL method). For Research Use Only
Specifications
Type
Recombinant Protein
Target
IGF1
Synonyms
IGF1 | IGF-IA | IGF-IB | IGFI | IBP1 | IGF-I | Insulin-like growth factor 1 | Insulin-like growth factor I | Insulin-like growth factor IA | Insulin-like growth factor IB | Mechano growth factor | Somatomedin-C | IGF1A | MGF
Species
Human
Modifications
Unmodified
Conjugations
Unconjugated
Region
49-118aa
Predicted Molecular Weight
7.6 kDa
AA Sequence
GPETLCGAELVDALQFVCGDRGFYFNKPTGYGSSSRRAPQTGIVDECCFRSCDLRRLEMYCAPLKPAKSA
Expression System
E. coli
Source Species
E. coli
Purification
Greater than 95% by SDS-PAGE
Usage Summary
The insulin-like growth factors, isolated from plasma, are structurally and functionally related to insulin but have a much higher growth-promoting activity. May be a physiological regulator of [1-14C]-2-deoxy-D-glucose (2DG) transport and glycogen synthesis in osteoblasts. Stimulates glucose transport in bone-derived osteoblastic (PyMS) cells and is effective at much lower concentrations than insulin, not only regarding glycogen and DNA synthesis but also with regard to enhancing glucose uptake. May play a role in synapse maturation
Bio-Activity
The ED50 as determined in a serum-free cell proliferation assay using MCF-7 human breast cancer cells is typically 1-15 ng/mL
Endotoxin
Less than 0.5 EU/µg protein (determined by LAL method).
Presentation
Lyophilized from 0.2 µm filtered 20 mM NaAc-Hac, pH 4.5
Storage
Store at -80°C for up to 1 year. Avoid freeze-thaw cycles.
Restrictions
For research use only. Intended for use by laboratory professionals.
About IGF1
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Images
Sodium Dodecyl Sulfate - Polyacrylamide Gel Electrophoresis
(Tris-Glycine gel) Discontinuous SDS-PAGE (reduced) with 5% enrichment gel and 15% separation gel.
Sodium Dodecyl Sulfate - Polyacrylamide Gel Electrophoresis
(Tris-Glycine gel) Discontinuous SDS-PAGE (reduced) with 5% enrichment gel and 15% separation gel.
Sodium Dodecyl Sulfate - Polyacrylamide Gel Electrophoresis
(Tris-Glycine gel) Discontinuous SDS-PAGE (reduced) with 5% enrichment gel and 15% separation gel.
Sodium Dodecyl Sulfate - Polyacrylamide Gel Electrophoresis
(Tris-Glycine gel) Discontinuous SDS-PAGE (reduced) with 5% enrichment gel and 15% separation gel.
Popular IGF1 Proteins
Source:
E. coli
Tag:
GST, N-terminus
Request SDS/MSDS
To request an SDS/MSDS form for this product, please contact our Technical Support department at:
Technical.Support@LSBio.com
Requested From: United States
Date Requested: 7/17/2024
Date Requested: 7/17/2024
