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| Catalog Number | Size | Price |
|---|---|---|
| LS-G3801-10 | 10 µg | $330 |
| LS-G3801-50 | 50 µg (1 mg/ml) | $463 |
Human FGF23 Protein (Recombinant Human IgG1 Fc) (aa1-251) - LS-G3801
Human FGF23 Protein (Recombinant Human IgG1 Fc) (aa1-251) - LS-G3801
Description:
FGF23 Protein LS-G3801 is a Recombinant Human FGF23 produced in HEK 293 Cells aa 1-251 with Human IgG1 Fc tag(s). It is low in endotoxin; Less than 0.1 EU/µg protein (determined by LAL method). For Research Use Only
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(800) 227-6666
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Overview
Description:
FGF23 Protein LS-G3801 is a Recombinant Human FGF23 produced in HEK 293 Cells aa 1-251 with Human IgG1 Fc tag(s). It is low in endotoxin; Less than 0.1 EU/µg protein (determined by LAL method). For Research Use Only
Specifications
Type
Recombinant Protein
Target
FGF23
Synonyms
FGF23 | ADHR | Fibroblast growth factor 23 | FGF-23 | HYPF | Phosphatonin | PHPTC | HPDR2
Species
Human
Modifications
Unmodified
Conjugations
Unconjugated
Tag
Human IgG1 Fc
Region
aa 1-251
Predicted Molecular Weight
60kDa-40kDa
Expression System
HEK 293 Cells
Source Species
Human
Purification
Greater than 90% by SDS-PAGE
Bio-Activity
Activates ERK and FRS2alpha phosphorylation in Klotho expressing cells.
Endotoxin
Less than 0.1 EU/µg protein (determined by LAL method).
Presentation
PBS
Storage
Store at 4°C for immediate use, or aliquot and store at -20°C for up to 3 months. Avoid freeze-thaw cycles.
Restrictions
For research use only. Intended for use by laboratory professionals.
About FGF23
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Images
Functional Assay
ERK and FRS2alpha phosphorylation induced by FGF-21 in Klotho expressing cells. Klotho expressing HEK 293EBNA cells were serum starved for 16 hours and then stimulated with hFGF-23-His, FGF-23-Fc and FGF-b (positive control) for 10 minutes, respectively. Antibodies against pFRS2alpha, pERK1/2 and total ERK1/2 were used for immunoblotting. Lane 1: Mock (non-treated) Lane 2: Mock + hFGF23-Fc 1 ug/ml Lane 3: Mock + hFGF23-His 1 ug/ml Lane 4: Klotho + hFGF23-Fc 1 ug/ml Lane 5: Klotho + hFGF23-Fc 4 ug/ml Lane 6: Klotho + mCD137-Fc 1 ug/ml Lane 7: Klotho (non-treated) Lane 8: Klotho + 100ng/ml FGF-b
Functional Assay
ERK and FRS2alpha phosphorylation induced by FGF-21 in Klotho expressing cells. Klotho expressing HEK 293EBNA cells were serum starved for 16 hours and then stimulated with hFGF-23-His, FGF-23-Fc and FGF-b (positive control) for 10 minutes, respectively. Antibodies against pFRS2alpha, pERK1/2 and total ERK1/2 were used for immunoblotting. Lane 1: Mock (non-treated) Lane 2: Mock + hFGF23-Fc 1 ug/ml Lane 3: Mock + hFGF23-His 1 ug/ml Lane 4: Klotho + hFGF23-Fc 1 ug/ml Lane 5: Klotho + hFGF23-Fc 4 ug/ml Lane 6: Klotho + mCD137-Fc 1 ug/ml Lane 7: Klotho (non-treated) Lane 8: Klotho + 100ng/ml FGF-b
Functional Assay
ERK and FRS2alpha phosphorylation induced by FGF-21 in Klotho expressing cells. Klotho expressing HEK 293EBNA cells were serum starved for 16 hours and then stimulated with hFGF-23-His, FGF-23-Fc and FGF-b (positive control) for 10 minutes, respectively. Antibodies against pFRS2alpha, pERK1/2 and total ERK1/2 were used for immunoblotting. Lane 1: Mock (non-treated) Lane 2: Mock + hFGF23-Fc 1 ug/ml Lane 3: Mock + hFGF23-His 1 ug/ml Lane 4: Klotho + hFGF23-Fc 1 ug/ml Lane 5: Klotho + hFGF23-Fc 4 ug/ml Lane 6: Klotho + mCD137-Fc 1 ug/ml Lane 7: Klotho (non-treated) Lane 8: Klotho + 100ng/ml FGF-b
Functional Assay
ERK and FRS2alpha phosphorylation induced by FGF-21 in Klotho expressing cells. Klotho expressing HEK 293EBNA cells were serum starved for 16 hours and then stimulated with hFGF-23-His, FGF-23-Fc and FGF-b (positive control) for 10 minutes, respectively. Antibodies against pFRS2alpha, pERK1/2 and total ERK1/2 were used for immunoblotting. Lane 1: Mock (non-treated) Lane 2: Mock + hFGF23-Fc 1 ug/ml Lane 3: Mock + hFGF23-His 1 ug/ml Lane 4: Klotho + hFGF23-Fc 1 ug/ml Lane 5: Klotho + hFGF23-Fc 4 ug/ml Lane 6: Klotho + mCD137-Fc 1 ug/ml Lane 7: Klotho (non-treated) Lane 8: Klotho + 100ng/ml FGF-b
Popular FGF23 Proteins
Request SDS/MSDS
To request an SDS/MSDS form for this product, please contact our Technical Support department at:
Technical.Support@LSBio.com
Requested From: United States
Date Requested: 11/25/2024
Date Requested: 11/25/2024
