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| Catalog Number | Size | Price |
|---|---|---|
| LS-G136702-10 | 10 µg | $356 |
| LS-G136702-50 | 50 µg | $698 |
| LS-G136702-500 | 500 µg | $2,385 |
| LS-G136702-1 | 1 mg | $3,404 |
Human CSF1 / MCSF Protein (Recombinant 6His, C-terminus) - LS-G136702
Human CSF1 / MCSF Protein (Recombinant 6His, C-terminus) - LS-G136702
Description:
CSF1 / MCSF Protein LS-G136702 is a Recombinant Human CSF1 / MCSF produced in Mammalian Cells 33-255aa with 6His, C-terminus tag(s). It is biologically active and is low in endotoxin; Less than 1.0 EU/µg protein (determined by LAL method). For Research Use Only
Toll Free North America
206-374-1102
206-374-1102For Research Use Only
Overview
Description:
CSF1 / MCSF Protein LS-G136702 is a Recombinant Human CSF1 / MCSF produced in Mammalian Cells 33-255aa with 6His, C-terminus tag(s). It is biologically active and is low in endotoxin; Less than 1.0 EU/µg protein (determined by LAL method). For Research Use Only
Specifications
Type
Recombinant Protein
Target
CSF1 / MCSF
Synonyms
CSF1 | CSF-1 | MCSF | M-CSF | Lanimostim | CSFM
Species
Human
Modifications
Unmodified
Conjugations
Unconjugated
Tag
6His, C-terminus
Region
33-255aa
Predicted Molecular Weight
26.17 kDa
AA Sequence
EEVSEYCSHMIGSGHLQSLQRLIDSQMETSCQITFEFVDQEQLKDPVCYLKKAFLLVQDIMEDTMRFRDNTPNAIAIVQLQELSLRLKSCFTKDYEEHDKACVRTFYETPLQLLEKVKNVFNETKNLLDKDWNIFSKNCNNSFAECSSQDVVTKPDCNCLYPKAIPSSDPASVSPHQPLAPSMAPVAGLTWEDSEGTEGSSLLPGEQPLHTVDPGSAKQRPPR
Expression System
Mammalian Cells
Source Species
Mammal
Purification
Greater than 95% by SDS-PAGE
Usage Summary
Cytokine that plays an essential role in the regulation of survival, proliferation and differentiation of hematopoietic precursor cells, especially mononuclear phagocytes, such as macrophages and monocytes. Promotes the release of proinflammatory chemokines, and thereby plays an important role in innate immunity and in inflammatory processes. Plays an important role in the regulation of osteoclast proliferation and differentiation, the regulation of bone resorption, and is required for normal bone development. Required for normal male and female fertility. Promotes reorganization of the actin cytoskeleton, regulates formation of membrane ruffles, cell adhesion and cell migration. Plays a role in lipoprotein clearance.
Bio-Activity
The ED50 as determined by its ability to acclerate M-NFS-60-dependent proliferation is less than 10 ng/ml
Endotoxin
Less than 1.0 EU/µg protein (determined by LAL method).
Presentation
Lyophilized from 0.2 µm filtered 20 mM PBs, pH 7.2, 150 mM NaCl
Storage
Store at -80°C for up to 1 year. Avoid freeze-thaw cycles.
Restrictions
For research use only. Intended for use by laboratory professionals.
About CSF1 / MCSF
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Images
Sodium Dodecyl Sulfate - Polyacrylamide Gel Electrophoresis
(Tris-Glycine gel) Discontinuous SDS-PAGE (reduced) with 5% enrichment gel and 15% separation gel.
Sodium Dodecyl Sulfate - Polyacrylamide Gel Electrophoresis
(Tris-Glycine gel) Discontinuous SDS-PAGE (reduced) with 5% enrichment gel and 15% separation gel.
Sodium Dodecyl Sulfate - Polyacrylamide Gel Electrophoresis
(Tris-Glycine gel) Discontinuous SDS-PAGE (reduced) with 5% enrichment gel and 15% separation gel.
Sodium Dodecyl Sulfate - Polyacrylamide Gel Electrophoresis
(Tris-Glycine gel) Discontinuous SDS-PAGE (reduced) with 5% enrichment gel and 15% separation gel.
Popular CSF1 / MCSF Proteins
Request SDS/MSDS
To request an SDS/MSDS form for this product, please contact our Technical Support department at:
Technical.Support@LSBio.com
Requested From: United States
Date Requested: 7/17/2024
Date Requested: 7/17/2024
