Login
Registration enables users to use special features of this website, such as past
order histories, retained contact details for faster checkout, review submissions, and special promotions.
order histories, retained contact details for faster checkout, review submissions, and special promotions.
Forgot password?
Registration enables users to use special features of this website, such as past
order histories, retained contact details for faster checkout, review submissions, and special promotions.
order histories, retained contact details for faster checkout, review submissions, and special promotions.
Quick Order
Products
Antibodies
ELISA and Assay Kits
Research Areas
Infectious Disease
Resources
Purchasing
Reference Material
Contact Us
Location
Corporate Headquarters
Vector Laboratories, Inc.
6737 Mowry Ave
Newark, CA 94560
United States
Telephone Numbers
Customer Service: (800) 227-6666 / (650) 697-3600
Contact Us
Additional Contact Details
Login
Registration enables users to use special features of this website, such as past
order histories, retained contact details for faster checkout, review submissions, and special promotions.
order histories, retained contact details for faster checkout, review submissions, and special promotions.
Forgot password?
Registration enables users to use special features of this website, such as past
order histories, retained contact details for faster checkout, review submissions, and special promotions.
order histories, retained contact details for faster checkout, review submissions, and special promotions.
Quick Order
| Catalog Number | Size | Price |
|---|---|---|
| LS-G3957-10 | 10 µg | $344 |
Human BAFF / TNFSF13B Protein (Recombinant Human IgG1 Fc) (aa136-285) - LS-G3957
Human BAFF / TNFSF13B Protein (Recombinant Human IgG1 Fc) (aa136-285) - LS-G3957
Description:
BAFF / TNFSF13B Protein LS-G3957 is a Recombinant Human BAFF / TNFSF13B produced in CHO Cells aa 136-285 with Human IgG1 Fc tag(s). It is low in endotoxin; Less than 0.01 EU/µg protein (determined by LAL method). For Research Use Only
Toll Free North America
(800) 227-6666
(800) 227-6666For Research Use Only
Overview
Description:
BAFF / TNFSF13B Protein LS-G3957 is a Recombinant Human BAFF / TNFSF13B produced in CHO Cells aa 136-285 with Human IgG1 Fc tag(s). It is low in endotoxin; Less than 0.01 EU/µg protein (determined by LAL method). For Research Use Only
Specifications
Type
Recombinant Protein
Target
BAFF / TNFSF13B
Synonyms
TNFSF13B | B-cell-activating factor | BAFF | ApoL related ligand TALL-1 | B-lymphocyte stimulator | CD257 | BLYS | Delta4 BAFF | Delta BAFF | TALL-1 | TALL1 | ZTNF4 | THANK | B lymphocyte stimulator | CD257 antigen | TNFSF20
Species
Human
Modifications
Unmodified
Conjugations
Unconjugated
Tag
Human IgG1 Fc
Region
aa 136-285
Predicted Molecular Weight
50kDa or 100kDa or 300kDa
Expression System
CHO Cells
Source Species
Hamster-Chinese
Purification
Greater than 95% by SDS-PAGE
Bio-Activity
Rescues the production of mature follicular and marginal zone B cells.-in vitro: Addition of 1-100 ng/ml of Fc-BAFF induces B cell survival in a dose-dependent manner.-in vivo: Fc-BAFF treatment rescues mature B cell development in BAFF deficient mice.
Endotoxin
Less than 0.01 EU/µg protein (determined by LAL method).
Presentation
Lyophilized from PBS
Reconstitution
Reconstitute with 100 µl sterile water.
Storage
Store lyophilized at -20°C for up to 6 months. Once reconstituted store at 4°C for immediate use.
Restrictions
For research use only. Intended for use by laboratory professionals.
About BAFF / TNFSF13B
Publications (0)
Customer Reviews (0)
Images
Functional Assay
Restoration of the splenic T and B cell architecture in Fc-BAFF injected BAFFdeficient mice. BAFF deficient mice were injected at day 0 with 100mg BAFF (human):Fc (human) (AG-40B-0120) intravenously and at day 14 with 50mg BAFF (human):Fc (human) intraperitoneal. At day 21, injected BAFFdeficient mice were sacrificed together with WT and control BAFFdeficient mice and splenic T and B cell architecture was analyzed by fluorescence microscopy on cryosections. A, Spleen sections of WT (left picture), BAFF deficient (middle picture) or injected BAFFdeficient mice (right picture) were stained for IgM (red) and CD90 (green). (B) Spleen sections of the same mice were stained for IgM (green) and MOMA (red).
Functional Assay
Restoration of the splenic T and B cell architecture in Fc-BAFF injected BAFFdeficient mice. BAFF deficient mice were injected at day 0 with 100mg BAFF (human):Fc (human) (AG-40B-0120) intravenously and at day 14 with 50mg BAFF (human):Fc (human) intraperitoneal. At day 21, injected BAFFdeficient mice were sacrificed together with WT and control BAFFdeficient mice and splenic T and B cell architecture was analyzed by fluorescence microscopy on cryosections. A, Spleen sections of WT (left picture), BAFF deficient (middle picture) or injected BAFFdeficient mice (right picture) were stained for IgM (red) and CD90 (green). (B) Spleen sections of the same mice were stained for IgM (green) and MOMA (red).
Functional Assay
Restoration of the splenic T and B cell architecture in Fc-BAFF injected BAFFdeficient mice. BAFF deficient mice were injected at day 0 with 100mg BAFF (human):Fc (human) (AG-40B-0120) intravenously and at day 14 with 50mg BAFF (human):Fc (human) intraperitoneal. At day 21, injected BAFFdeficient mice were sacrificed together with WT and control BAFFdeficient mice and splenic T and B cell architecture was analyzed by fluorescence microscopy on cryosections. A, Spleen sections of WT (left picture), BAFF deficient (middle picture) or injected BAFFdeficient mice (right picture) were stained for IgM (red) and CD90 (green). (B) Spleen sections of the same mice were stained for IgM (green) and MOMA (red).
Functional Assay
Restoration of the splenic T and B cell architecture in Fc-BAFF injected BAFFdeficient mice. BAFF deficient mice were injected at day 0 with 100mg BAFF (human):Fc (human) (AG-40B-0120) intravenously and at day 14 with 50mg BAFF (human):Fc (human) intraperitoneal. At day 21, injected BAFFdeficient mice were sacrificed together with WT and control BAFFdeficient mice and splenic T and B cell architecture was analyzed by fluorescence microscopy on cryosections. A, Spleen sections of WT (left picture), BAFF deficient (middle picture) or injected BAFFdeficient mice (right picture) were stained for IgM (red) and CD90 (green). (B) Spleen sections of the same mice were stained for IgM (green) and MOMA (red).
Request SDS/MSDS
To request an SDS/MSDS form for this product, please contact our Technical Support department at:
Technical.Support@LSBio.com
Requested From: United States
Date Requested: 11/22/2024
Date Requested: 11/22/2024
