Products
Research Areas
COVID-19
Resources
Login
Quick Order
Cart Cart lightblue
Login
Registration enables users to use special features of this website, such as past
order histories, retained contact details for faster checkout, review submissions, and special promotions.


Fields marked with a * are required.

Login
Quick Order
Contact Us

Locations


Orders Processing,
Shipping & Receiving,
Warehouse

2 Shaker Rd Suites
B001/B101
Shirley, MA 01464


Production Lab

Floor 6, Suite 620
20700 44th Avenue W
Lynnwood, WA 98036

Telephone Numbers



Tel: +1 (800) 227-6666


Contact Us



Additional Contact Details

Login
Registration enables users to use special features of this website, such as past
order histories, retained contact details for faster checkout, review submissions, and special promotions.


Fields marked with a * are required.

Login
Quick Order
PathPlusTM SORT1 / Sortilin Antibodies
SORT1 (Sortilin) is a protein that functions as a sorting receptor in the Golgi compartment and as a clearance receptor on the cell surface. It is required for protein transport from the Golgi apparatus to the lysosomes by a pathway that is independent of the mannose-6-phosphate receptor (M6PR), and is also required for protein transport from the Golgi apparatus to the endosomes. In the nervous system, SORT1 promotes neuronal apoptosis by mediating endocytosis of the proapoptotic precursor forms of BDNF (proBDNF) and NGFB (proNGFB). It also acts as a receptor for neurotensin. It may promote mineralization of the extracellular matrix during osteogenic differentiation by scavenging extracellular LPL. It is likely required in adipocytes for the formation of specialized storage vesicles containing the glucose transporter SLC2A4/GLUT4 (GLUT4 storage vesicles, or GSVs). These vesicles provide a stable pool of SLC2A4 and confer increased responsiveness to insulin. References: The UniProt Consortium. Nucleic Acids Res. 47: D506-515 (2019); Nucleic Acids Res. 2016 Jan 4;44(D1):D733-45, PMID:26553804

1 PathPlusTM Antibody
☰ Filters
Antibodies (1)
Primary (1)
SORT1 / Sortilin (1)
Human (1)
IHC-P (1)
ELISA (1)
rabbit (1)
Product Group
PathPlus Neuro (1)
IgG (1)
polyclonal pc (1)
Unconjugated (1)
No (1)
SORT1 / Sortilin Antibody - Human Brain, Cerebellum: Formalin-Fixed, Paraffin-Embedded (FFPE)
Select
Neuroscience
SORT1 / Sortilin Rabbit anti-Human Polyclonal Antibody
Human
ELISA, IHC-P
Unconjugated
50 µg/$460
Viewing 1-1 of 1 product results