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Antibodies
ELISA and Assay Kits
Research Areas
Infectious Disease
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Corporate Headquarters
Vector Laboratories, Inc.
6737 Mowry Ave
Newark, CA 94560
United States
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Customer Service: (800) 227-6666 / (650) 697-3600
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Registration enables users to use special features of this website, such as past
order histories, retained contact details for faster checkout, review submissions, and special promotions.
order histories, retained contact details for faster checkout, review submissions, and special promotions.
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order histories, retained contact details for faster checkout, review submissions, and special promotions.
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PathPlusTM SMO / Smoothened Antibodies
SMO (Smoothened) is a Frizzled Receptor that associates with the Patched protein to mediate the cellular response to the Hedgehog secreted protein signal. This controls patterning and growth during vertebrate development. SMO is activated in a number of human tumors. It can function as an oncogene in basal-cell carcinomas, and is a target of various inhibition therapies. In immunohistochemistry, SMO has moderate membranous and cytoplasmic positivity in a majority of tissues throughout the body.
References: Cancers (Basel). 2016 Feb; 8(2): 22, PMID: 26891329
1 PathPlusTM Antibody
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Antibodies
(1)
Type
Primary
(1)
Target
SMO / Smoothened
(1)
Reactivity
Human
(1)
Mouse
(1)
Application
IHC
(1)
IHC-P
(1)
IF
(1)
Host
rabbit
(1)
Product Group
GPCR Database Antibodies
(1)
PathPlus Cancer
(1)
Clonality
polyclonal pc
(1)
Format
Unconjugated
(1)
Epitope
1st Extracellular Domain
(1)
Publications
Yes
(1)
Cancer
SMO / Smoothened Rabbit anti-Human Polyclonal (1st Extracellular Domain) Antibody
Mouse, Human
IF, IHC, IHC-P
Unconjugated
50 µg/$460
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