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PathPlusTM SLC2A1 / GLUT-1 Antibodies
SLC2A1 (also known as GLUT1) is a facilitative glucose transporter protein involved in constitutive or basal glucose uptake. It is capable of transporting a wide range of aldoses, including both pentoses and hexoses, across the plasma membrane. SLC2A1 mutations lead to GLUT1 deficiency syndrome 1 and 2, dystonia, idiopathic generalized epilepsy and stomatin-deficient cryohydrocytosis. GLUT1 is also relevant to Alzheimer’s disease and neurodegenerative disorders, as lower levels of GLUT1 have been found to contribute to vascular degeneration, diminished neuronal activity, reductions in blood flow and blood-brain barrier degeneration. In immunohistochemistry, SLC2A1 has highest cytoplasmic positivity in trophoblasts, erythrocytes, and endothelial cells in the blood-brain barrier, and also has lower levels of staining in most other tissues. References: Annual Review of Nutrition. 16: 235–56, PMID: 8839927; Nucleic Acids Research. 45 (D1): D158–D169. January 2017, PMID: 27899622; Pflügers Archiv. 2004. 447 (5): 480–9, PMID: 12750891; Nat Neurosci. 2015 Apr;18(4):521-530, PMID: 25730668;

2 PathPlusTM Antibodies
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Antibodies (2)
Primary (2)
SLC2A1 / GLUT-1 (2)
Human (2)
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rabbit (1)
mouse (1)
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monoclonal mc (1)
polyclonal pc (1)
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SLC2A1 / GLUT-1 Antibody - Anti-SLC2A1 / GLUT1 antibody IHC of human colon, erythrocytes. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 5 ug/ml.
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Neuroscience
Cancer Pathology
SLC2A1 / GLUT-1 Rabbit anti-Human Polyclonal (C-Terminus) Antibody
Rat, Human
IF, IHC, IHC-P, WB
Unconjugated
50 µl/$545
SLC2A1 / GLUT-1 Antibody - Human Kidney: Formalin-Fixed, Paraffin-Embedded (FFPE)
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Neuroscience
Cancer Pathology
SLC2A1 / GLUT-1 Mouse anti-Human Monoclonal (Concentrated) Antibody
Human
IHC-Fr, IHC-P
Unconjugated, Concentrated
0.05 ml/$460
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