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PathPlusTM GPR68 / OGR1 Antibodies
G protein-coupled receptor 68 (GPR68) is a proton-sensing receptor involved in pH homeostasis. GPR68 represents an osteoblastic pH sensor regulating cell-mediated responses to acidosis in bone. GPR68 mediates its action by association with G proteins that stimulates inositol phosphate (IP) production or Ca2+ mobilization. The receptor is almost silent at pH 7.8 but fully activated at pH 6.8. GPR68 also functions as a metastasis suppressor in prostate cancer.
References: The UniProt Consortium. Nucleic Acids Res. 47: D506-515 (2019); Nucleic Acids Res. 2016 Jan 4;44(D1):D733-45, PMID:26553804
1 PathPlusTM Antibody
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Neuroscience
GPR68 / OGR1 Rabbit anti-Human Polyclonal (C-Terminus) Antibody
Rabbit, Mouse, Bovine, Rat, Hamster, Pig, Horse, Human, Monkey
IHC-P
Unconjugated
50 µg/$440
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