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CD47
CD47 molecule
Has a role in both cell adhesion by acting as an adhesion receptor for THBS1 on platelets, and in the modulation of integrins. Plays an important role in memory formation and synaptic plasticity in the hippocampus (By similarity). Receptor for SIRPA, binding to which prevents maturation of immature dendritic cells and inhibits cytokine production by mature dendritic cells. Interaction with SIRPG mediates cell-cell adhesion, enhances superantigen-dependent T-cell-mediated proliferation and costimulates T-cell activation. May play a role in membrane transport and/or integrin dependent signal transduction. May prevent premature elimination of red blood cells. May be involved in membrane permeability changes induced following virus infection.
| Gene Name: | CD47 molecule |
| Synonyms: | CD47, CD47 antigen, CD47 molecule, Integrin associated protein, Integrin-associated protein, Leukocyte surface antigen CD47, MER6, Protein MER6, Rh-related antigen, OA3, CD47 glycoprotein, IAP |
| Target Sequences: | NM_001777 NP_001768.1 Q08722 |
Publications (3)
1
CD47 is an adverse prognostic factor and a therapeutic target in gastric cancer. Yoshida K, Tsujimoto H, Matsumura K, Kinoshita M, Takahata R, Matsumoto Y, Hiraki S, Ono S, Seki S, Yamamoto J, Hase K. Cancer medicine. 2015 4:1322-33. (IP; Human)
[Full Text Article]
[PubMed:26077800]
[PMC:PMC4567017]
2
Expression of CD47 antigen in Reed-Sternberg cells as a new potential biomarker for classical Hodgkin lymphoma. B López-Pereira, A A Fernández-Velasco, I Fernández-Vega, D Corte-Torres, C Quirós, J A Villegas, P Palomo, S González, A P González, Á Payer, T Bernal, M A Moro-García, R Alonso-Arias, S Alonso-Álvarez, E Colado. Clinical & translational oncology : official publication of the Federation of Spanish Oncology Societies and of the National Cancer Institute of Mexico. 2020 May;22:782-785. [Full Text Article]
[PubMed:31359339]
3
Checkpoint CD47 expression in classical Hodgkin lymphoma. Alex Reza Gholiha, Peter Hollander, Liza Löf, Ingrid Glimelius, Gustaf Hedstrom, Daniel Molin, Henrik Hjalgrim, Karin E Smedby, Jamileh Hashemi, Rose-Marie Amini, Gunilla Enblad. British journal of haematology. 2022 June;197:580-589. [Full Text Article]
[PubMed:35301709]
[PMC:PMC9310712]
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CD47 Rabbit anti-Human Polyclonal Antibody
Mouse, Rat
IF, IHC, IHC-P, WB
Unconjugated
50 µl/$460
CD47 Rabbit anti-Human Polyclonal (aa288-315) Antibody
Human
IHC, IHC-P, WB
Unconjugated
200 µl/$460
CD47 Rabbit anti-Human Polyclonal (aa23-140) Antibody
Human
ELISA, IHC, IHC-P
Unconjugated
50 µg/$460
CD47 Rabbit anti-Human Polyclonal Antibody
Mouse, Rat, Human
ELISA, Flo, IF, IHC-P, WB
Unconjugated
100 µg/$575
CD47 Mouse anti-Human Monoclonal (Azide-free) (B6H12.2) Antibody
Human
Flo
Unconjugated, Azide-free
100 µg/$386
CD47 Mouse anti-Human Monoclonal (Preservative Free) (07) Antibody
Human
Flo
Unconjugated, Preservative Free
100 µl/$412
CD47 Rabbit anti-Mouse Polyclonal (aa18-219) Antibody
Mouse
WB
Unconjugated
100 µl/$306; 200 µl/$347; 500 µl/$484; 1 ml/$553; 2 ml/$737; 5 ml/$1,206
Sandwich
96-Well Strip Plate
Mouse
0.312 - 20 ng/ml
Colorimetric - 450nm (TMB)
Cell Culture Supernatants, Cell Lysates, Plasma, Serum, Tissue Homogenates
1 Plate/$748
Sandwich
96-Well Strip Plate
Human
125 - 8000 pg/ml
Colorimetric - 450nm (TMB)
Cell Culture Supernatants, Serum
1 Plate/$624
CD47 Mouse anti-Human Monoclonal (Azide-free, Low Endotoxin) (MIAP410) Antibody
Mouse, Rat, Human
Flo, ICC, IF, IHC, IP, WB
Unconjugated, Azide-free, Low Endotoxin
50 µg/$248; 500 µg/$333; 1 mg/$433
E. coli
6His, N-terminus
23.9 kDa
10 µg/$267; 50 µg/$352; 100 µg/$562; 200 µg/$702; 1 mg/$1,723; 500 µg/$1,298; 5 mg/$2,673; 2 mg/$1,900
CD47 Mouse anti-Human Monoclonal (IAP/964 + B6H12.2) Antibody
Mouse, Human
Flo, IF, IHC, IHC-P
Unconjugated
20 µg/$371; 100 µg/$574
CD47 Mouse anti-Human Monoclonal (BRIC126) Antibody
Human
Flo, IHC, IHC-Fr, IP, WB
Unconjugated
25 µg/$281; 0.2 mg/$471
CD47 Mouse anti-Human Monoclonal (1/1A4) Antibody
Human
Flo, IHC, IHC-Fr, IP
Unconjugated
0.1 mg/$385; 0.2 mg/$471
CD47 Mouse anti-Monkey Monoclonal (MEM-122) Antibody
Porcine, Non-Human Primates, Human
Flo, IHC, IHC-Fr, WB
Unconjugated
0.1 mg/$309
CD47 Mouse anti-Human Monoclonal (B6H12) Antibody
Human
Flo
Unconjugated
100 µl/$434
CD47 Mouse anti-Human Monoclonal (AF488) (MIAP410) Antibody
Mouse, Rat, Human
Flo
AF488 Conjugated
20 Tests/$268; 100 Tests/$353; 200 Tests/$423
CD47 Mouse anti-Human Monoclonal (Low Endotoxin) (1/1A4) Antibody
Human
Flo, IHC, IHC-Fr, IP
Unconjugated, Low Endotoxin
0.5 mg/$671
CD47 Mouse anti-Human Monoclonal (AF488) (CC2C6D4) Antibody
Human
Flo
AF488 Conjugated
20 Tests/$256; 100 Tests/$306; 200 Tests/$353
CD47 Mouse anti-Human Monoclonal (FITC) (B6H12) Antibody
Human
Flo
FITC Conjugated
25 µg/$288; 100 µg/$414
CD47 Rabbit anti-Human Polyclonal Antibody
Human, Crab-eating macaque
ELISA, ICC, IF, IHC-P
Unconjugated
20 µl/$256; 100 µl/$412
CD47 Mouse anti-Human Monoclonal (PE) (07) Antibody
Human
Flo
PE Conjugated
25 Tests/$278; 100 Tests/$376
CD47 Mouse anti-Human Monoclonal (B6H12.2) Antibody
Human
Block, Flo, Func, IF, IHC, IHC-P, WB
Unconjugated
20 µg/$371; 100 µg/$574
CD47 Rabbit anti-Human Monoclonal (Preservative Free) (006) Antibody
Human
ELISA
Unconjugated, Preservative Free
100 µl/$412
CD47 Mouse anti-Human Monoclonal (IAP/964) Antibody
Mouse, Human
Flo, IF, IHC, IHC-P
Unconjugated
20 µg/$371; 100 µg/$574
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