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| Catalog Number | Size | Price |
|---|---|---|
| LS-A9077-50 | 50 µg (1 mg/ml) | $440 |
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PathPlus™ Polyclonal Rabbit anti‑Human WNT10A Antibody (Internal, IHC) LS‑A9077
PathPlus™ Polyclonal Rabbit anti‑Human WNT10A Antibody (Internal, IHC) LS‑A9077
Antibody:
WNT10A Rabbit anti-Human Polyclonal (Internal) Antibody
Application:
IHC, IHC-P
Reactivity:
Human, Monkey, Bovine, Dog
Format:
Unconjugated, Unmodified
Overview
Antibody:
WNT10A Rabbit anti-Human Polyclonal (Internal) Antibody
Application:
IHC, IHC-P
Reactivity:
Human, Monkey, Bovine, Dog
Format:
Unconjugated, Unmodified
Specifications
Description
The WNT gene family consists of structurally related genes which encode secreted signaling proteins. These proteins have been implicated in oncogenesis and in several developmental processes, including regulation of cell fate and patterning during embryogenesis. This gene is a member of the WNT gene family. It is strongly expressed in the cell lines of promyelocytic leukemia and Burkitt's lymphoma. In addition, it and another family member, the WNT6 gene, are strongly coexpressed in colorectal cancer cell lines. The gene overexpression may play key roles in carcinogenesis through activation of the WNT-beta-catenin-TCF signaling pathway. This gene and the WNT6 gene are clustered in the chromosome 2q35 region.
References: The UniProt Consortium. Nucleic Acids Res. 47: D506-515 (2019); Nucleic Acids Res. 2016 Jan 4;44(D1):D733-45, PMID:26553804
Target
Human WNT10A
Synonyms
WNT10A | SSPS | STHAG4 | OODD | Protein Wnt-10a
Host
Rabbit
Reactivity
Human, Monkey, Bovine, Dog
(tested or 100% immunogen sequence identity)
Predicted
Mouse, Rat, Bat, Hamster, Rabbit (at least 90% immunogen sequence identity)
Clonality
Polyclonal
Conjugations
Unconjugated
Purification
Immunoaffinity purified
Modifications
Unmodified
Immunogen
Synthetic 16 amino acid peptide from internal region of human WNT10A. Percent identity with other species by BLAST analysis: Human, Gorilla, Gibbon, Monkey, Marmoset, Elephant, Dog, Bovine (100%); Mouse, Rat, Hamster, Bat, Rabbit (94%); Opossum (81%).
Epitope
Internal
Specificity
Human WNT10A. BLAST analysis of the peptide immunogen showed no homology with other human proteins.
Applications
- IHC
- IHC - Paraffin (5 µg/ml)
|
Performing IHC? See our complete line of Immunohistochemistry Reagents including antigen retrieval solutions, blocking agents
ABC Detection Kits and polymers, biotinylated secondary antibodies, substrates and more.
|
Presentation
PBS, 0.1% Sodium Azide
Storage
Aliquot and store undiluted at -20°C or below for up to 1 year. Can be stored undiluted at 4°C for up to 1 month. Avoid freeze-thaw cycles.
Restrictions
For research use only. Intended for use by laboratory professionals.
About WNT10A
Validation
Non-Hodgkin's lymphoma
Non-Hodgkin's lymphoma
Ovary, carcinoma
Ovary, carcinoma
Skin, Malignant Melanoma
Skin, Malignant Melanoma
Human Stomach: Formalin-Fixed, Paraffin-Embedded (FFPE)
Human Stomach: Formalin-Fixed, Paraffin-Embedded (FFPE)
Anti-WNT10A antibody IHC of human pancreas, islet. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.
Anti-WNT10A antibody IHC of human pancreas, islet. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.
Human Melanoma (Lymph Node): Formalin-Fixed, Paraffin-Embedded (FFPE)
Human Melanoma (Lymph Node): Formalin-Fixed, Paraffin-Embedded (FFPE)
Human Prostate: Formalin-Fixed, Paraffin-Embedded (FFPE)
Human Prostate: Formalin-Fixed, Paraffin-Embedded (FFPE)
See More About...
LSBio Ratings
PathPlus™ WNT10A Antibody (Internal) for IHC LS-A9077 has an LSBio Rating of
Laboratory Validation Score (5)
Learn more about The LSBio Ratings Algorithm
Publications (0)
Customer Reviews (0)
Featured Products
Species:
Human, Monkey, Bat, Bovine, Dog, Rabbit
Applications:
IHC, IHC - Paraffin
Species:
Mouse, Human
Applications:
IHC, IHC - Paraffin, Western blot
Species:
Human, Monkey, Mouse, Rat, Bovine, Dog, Hamster, Rabbit
Applications:
IHC, IHC - Paraffin
Species:
Human, Mouse, Rat
Applications:
IHC, Immunofluorescence, Western blot, ELISA
Request SDS/MSDS
To request an SDS/MSDS form for this product, please contact our Technical Support department at:
Technical.Support@LSBio.com
Requested From: United States
Date Requested: 11/22/2024
Date Requested: 11/22/2024
