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| Catalog Number | Size | Price |
|---|---|---|
| LS-B14330-50 | 50 µl (1 mg/ml) | $460 |
PathPlus™ Polyclonal Rabbit anti‑Human TPSAB1 / Mast Cell Tryptase Antibody (IHC, IF, WB) LS‑B14330
PathPlus™ Polyclonal Rabbit anti‑Human TPSAB1 / Mast Cell Tryptase Antibody (IHC, IF, WB) LS‑B14330
Note: This antibody replaces LS-C341410
Antibody:
TPSAB1 / Mast Cell Tryptase Rabbit anti-Human Polyclonal Antibody
Application:
IHC, IHC-P, IF, WB
Reactivity:
Human
Format:
Unconjugated, Unmodified
Toll Free North America
(800) 227-6666
(800) 227-6666For Research Use Only
Overview
Antibody:
TPSAB1 / Mast Cell Tryptase Rabbit anti-Human Polyclonal Antibody
Application:
IHC, IHC-P, IF, WB
Reactivity:
Human
Format:
Unconjugated, Unmodified
Specifications
Description
Tryptase alpha/beta 1 (TPSAB1) is one of two adjacent genes (TPSAB1, TPSB2) that code for mast cell tryptase, a serine protease. Mast cell tryptase is the predominant isoenzyme in mast cells. It is often used as a marker for mast cell activation, and high levels of tryptase can be an indicator of anaphylaxis, mastocytosis or the presence of eosinophilic leukemia. In immunohistochemistry, antibodies to mast cell tryptase stain secretory granules of mast cells.
References: J Biol Chem. 1999. 274 (6): 3355–62,PMID: 9920877; Nat Genet. 2016 Dec;48(12):1564-1569, PMID: 27749843; Proceedings of the National Academy of Sciences of the United States of America. 1990 May. 87 (10): 3811–5, PMID: 2187193; Cancer Research. 2017 Mar. 77 (6): 1261–1270, PMID: 28254862; Am. J. Clin. Path. 2015 Sept. 144 (3): 377–92, PMID 26276769; Anaesthesia. 2004 Jul;59(7):695-703, PMID: 15200544
Target
Human TPSAB1 / Mast Cell Tryptase
Synonyms
TPSAB1 | Alpha tryptase | Mast cell alpha II tryptase | Tryptase alpha-1 | Tryptase beta I | Tryptase-III | TPSB1 | Tryptase alpha II | TPS1 | TPS2 | Tryptase beta-1 | Tryptase-1 | Tryptase-I | Mast cell beta I tryptase | Tryptase alpha/beta 1 | Tryptase alpha/beta-1 | Tryptase beta 1 | Tryptase I
Host
Rabbit
Reactivity
Human
(tested or 100% immunogen sequence identity)
Clonality
Polyclonal
Conjugations
Unconjugated
Purification
Immunoaffinity purified
Modifications
Unmodified
Immunogen
Recombinant full length Human TPSAB1.
Specificity
Human TPSAB1 / Mast Cell Tryptase
Applications
- IHC
- IHC - Paraffin (2.5 - 5 µg/ml)
- Immunofluorescence (1:50 - 1:200)
- Western blot (1:500 - 1:2000)
|
Performing IHC? See our complete line of Immunohistochemistry Reagents including antigen retrieval solutions, blocking agents
ABC Detection Kits and polymers, biotinylated secondary antibodies, substrates and more.
|
Presentation
PBS, 0.1% Sodium Azide, 50% Glycerol
Storage
Short term: store at 4°C. Long term: aliquot and store at -20°C. Avoid freeze-thaw cycles.
Restrictions
For research use only. Intended for use by laboratory professionals.
About TPSAB1 / Mast Cell Tryptase
Validation
Human Colon, mast cells: Formalin-Fixed, Paraffin-Embedded (FFPE)
Human Colon, mast cells: Formalin-Fixed, Paraffin-Embedded (FFPE)
See More About...
LSBio Ratings
PathPlus™ TPSAB1 / Mast Cell Tryptase Antibody for IHC, IF/Immunofluorescence, WB/Western LS-B14330 has an LSBio Rating of
Laboratory Validation Score (5)
Learn more about The LSBio Ratings Algorithm
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Species:
Human, Monkey, Cat, Dog
Applications:
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Species:
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Applications:
IHC, IHC - Paraffin
Species:
Human
Applications:
IHC - Paraffin
Species:
Human
Applications:
IHC, IHC - Paraffin, IHC - Frozen, Immunofluorescence, ELISA
Species:
Human, Monkey, Cat, Dog
Applications:
IHC, IHC - Paraffin, IHC - Frozen, Western blot, ELISA
Species:
Mouse
Applications:
Western blot, Immunoprecipitation
Request SDS/MSDS
To request an SDS/MSDS form for this product, please contact our Technical Support department at:
Technical.Support@LSBio.com
Requested From: United States
Date Requested: 11/22/2024
Date Requested: 11/22/2024
