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| Catalog Number | Size | Price |
|---|---|---|
| LS-B16154-100 | 100 µl (1 mg/ml) | $460 |
PathPlus™ Monoclonal Mouse anti‑Human TPSAB1 / Mast Cell Tryptase Antibody (clone ABT‑MCT, IHC) LS‑B16154
PathPlus™ Monoclonal Mouse anti‑Human TPSAB1 / Mast Cell Tryptase Antibody (clone ABT‑MCT, IHC) LS‑B16154
Note: This antibody replaces LS-C744533
Antibody:
TPSAB1 / Mast Cell Tryptase Mouse anti-Human Monoclonal (ABT-MCT) Antibody
Application:
IHC, IHC-P
Reactivity:
Human
Format:
Unconjugated, Unmodified
Toll Free North America
(800) 227-6666
(800) 227-6666For Research Use Only
Overview
Antibody:
TPSAB1 / Mast Cell Tryptase Mouse anti-Human Monoclonal (ABT-MCT) Antibody
Application:
IHC, IHC-P
Reactivity:
Human
Format:
Unconjugated, Unmodified
Specifications
Description
Tryptase alpha/beta 1 (TPSAB1) is one of two adjacent genes (TPSAB1, TPSB2) that code for mast cell tryptase, a serine protease. Mast cell tryptase is the predominant isoenzyme in mast cells. It is often used as a marker for mast cell activation, and high levels of tryptase can be an indicator of anaphylaxis, mastocytosis or the presence of eosinophilic leukemia. In immunohistochemistry, antibodies to mast cell tryptase stain secretory granules of mast cells.
References: J Biol Chem. 1999. 274 (6): 3355–62,PMID: 9920877; Nat Genet. 2016 Dec;48(12):1564-1569, PMID: 27749843; Proceedings of the National Academy of Sciences of the United States of America. 1990 May. 87 (10): 3811–5, PMID: 2187193; Cancer Research. 2017 Mar. 77 (6): 1261–1270, PMID: 28254862; Am. J. Clin. Path. 2015 Sept. 144 (3): 377–92, PMID 26276769; Anaesthesia. 2004 Jul;59(7):695-703, PMID: 15200544
Target
Human TPSAB1 / Mast Cell Tryptase
Synonyms
TPSAB1 | Alpha tryptase | Mast cell alpha II tryptase | Tryptase alpha-1 | Tryptase beta I | Tryptase-III | TPSB1 | Tryptase alpha II | TPS1 | TPS2 | Tryptase beta-1 | Tryptase-1 | Tryptase-I | Mast cell beta I tryptase | Tryptase alpha/beta 1 | Tryptase alpha/beta-1 | Tryptase beta 1 | Tryptase I
Host
Mouse
Reactivity
Human
(tested or 100% immunogen sequence identity)
Clonality
IgG
Monoclonal
Clone
ABT-MCT
Conjugations
Unconjugated
Purification
Affinity purified
Modifications
Unmodified
Immunogen
Synthetic Mast cell tryptase
Applications
- IHC (1:200 - 1:400)
- IHC - Paraffin (1:50)
|
Performing IHC? See our complete line of Immunohistochemistry Reagents including antigen retrieval solutions, blocking agents
ABC Detection Kits and polymers, biotinylated secondary antibodies, substrates and more.
|
Usage
Use Heat-induced epitope retrieval (HIER) Citrate buffer of pH 6.0 Recommended IHC controls tissues are Cytoplasmic, . Resulting localization is Cytoplasmic
Presentation
0.5% BSA, 0.1% Kathon, Tris-Buffered Saline, DI H2O and 50% glycerol
Storage
Store at -20°C for up to 1 year.
Restrictions
For research use only. Intended for use by laboratory professionals.
About TPSAB1 / Mast Cell Tryptase
Validation
Human Placenta: Formalin-Fixed, Paraffin-Embedded (FFPE)
Human Placenta: Formalin-Fixed, Paraffin-Embedded (FFPE)
See More About...
LSBio Ratings
PathPlus™ TPSAB1 / Mast Cell Tryptase Antibody (clone ABT-MCT) for IHC LS-B16154 has an LSBio Rating of
Laboratory Validation Score (5)
Learn more about The LSBio Ratings Algorithm
Publications (0)
Customer Reviews (0)
Featured Products
Species:
Human
Applications:
IHC, IHC - Paraffin, Immunofluorescence, Western blot
Species:
Human, Monkey, Cat, Dog
Applications:
IHC, IHC - Paraffin, Western blot
Species:
Human
Applications:
IHC - Paraffin
Species:
Human
Applications:
IHC, IHC - Paraffin, IHC - Frozen, Immunofluorescence, ELISA
Species:
Human, Monkey, Cat, Dog
Applications:
IHC, IHC - Paraffin, IHC - Frozen, Western blot, ELISA
Species:
Mouse
Applications:
Western blot, Immunoprecipitation
Request SDS/MSDS
To request an SDS/MSDS form for this product, please contact our Technical Support department at:
Technical.Support@LSBio.com
Requested From: United States
Date Requested: 11/22/2024
Date Requested: 11/22/2024
