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| Catalog Number | Size | Price |
|---|---|---|
| LS-B9626-200 | 200 µl (1 mg/ml) | $460 |
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2 of 2
PathPlus™ Polyclonal Rabbit anti‑Human TIAM1 Antibody (aa1478‑1506, IHC, WB) LS‑B9626
PathPlus™ Polyclonal Rabbit anti‑Human TIAM1 Antibody (aa1478‑1506, IHC, WB) LS‑B9626
Note: This antibody replaces LS-C156218
Antibody:
TIAM1 Rabbit anti-Human Polyclonal (aa1478-1506) Antibody
Application:
IHC, IHC-P, WB
Reactivity:
Human
Format:
Unconjugated, Unmodified
Toll Free North America
(800) 227-6666
(800) 227-6666For Research Use Only
Overview
Antibody:
TIAM1 Rabbit anti-Human Polyclonal (aa1478-1506) Antibody
Application:
IHC, IHC-P, WB
Reactivity:
Human
Format:
Unconjugated, Unmodified
Specifications
Description
TIAM1 is a guanine nucleotide exchange factor involved in cell migration and regulation of cell shape. TIAM1 is found in effectively all tumor cell lines, and upregulation of TIAM1 has been suggested to promote proliferation, invasion and metastases in various cancers, including colorectal and renal carcinoma, pancreatic cancer, chondrosarcoma, T-cell lymphoma, and breast cancer. In immunohistochemistry of normal tissue, TIAM1 has cytoplasmic and membranous staining in immune cells and in the cerebellum.
References: J Cell Biol. 2000 Jul 10;150(1):177-91, PMID: 10893266, J Biol Chem. 2001 Nov 9;276(45):41889-97, PMID: 11551917; Biorheology. 2003;40(1-3):93-100, PMID: 12454392, PMID: World J Gastroenterol. 2005 Feb 7; 11(5): 705–707, PMID: 15655826, Oncogene. 2010 Dec 16;29(50):6533-42, PMID: 20802514; Mol Cancer Res. 2013 Mar;11(3):230-9; J Cell Biol. 2012 Oct 15;199(2):331-45, PMID: 23071154; J Cell Sci. 2004 Sep 15;117(Pt 20):4863-71, PMID: 15340013
Host
Rabbit
Reactivity
Human
(tested or 100% immunogen sequence identity)
Predicted
Mouse (at least 90% immunogen sequence identity)
Clonality
Polyclonal
Conjugations
Unconjugated
Purification
Protein A purified
Modifications
Unmodified
Epitope
aa1478-1506
Specificity
This TIAM1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 1478-1506 amino acids from the C-terminal region of human TIAM1.
Applications
- IHC
- IHC - Paraffin (1:100)
- Western blot (1:1000)
|
Performing IHC? See our complete line of Immunohistochemistry Reagents including antigen retrieval solutions, blocking agents
ABC Detection Kits and polymers, biotinylated secondary antibodies, substrates and more.
|
Presentation
PBS, 0.05% Proclin300.
Storage
Maintain refrigerated at 2°C to 8°C for up to 6 months. For long term storage store at -20°C.
Restrictions
For research use only. Intended for use by laboratory professionals.
About TIAM1
Validation
Anti-TIAM1 antibody IHC staining of human colon. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody dilution 1:100.
Anti-TIAM1 antibody IHC staining of human colon. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody dilution 1:100.
See More About...
LSBio Ratings
PathPlus™ TIAM1 Antibody (aa1478-1506) for IHC, WB/Western LS-B9626 has an LSBio Rating of
Laboratory Validation Score (5)
Learn more about The LSBio Ratings Algorithm
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Featured Products
Source:
E. coli
Tag:
His-GST
Request SDS/MSDS
To request an SDS/MSDS form for this product, please contact our Technical Support department at:
Technical.Support@LSBio.com
Requested From: United States
Date Requested: 11/27/2024
Date Requested: 11/27/2024
