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Registration enables users to use special features of this website, such as past
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| Catalog Number | Size | Price |
|---|---|---|
| LS-B11448-50 | 50 µg (0.5 mg/ml) | $460 |
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PathPlus™ Monoclonal Mouse anti‑Human MPO / Myeloperoxidase Antibody (clone 3E11, IHC, WB) LS‑B11448
PathPlus™ Monoclonal Mouse anti‑Human MPO / Myeloperoxidase Antibody (clone 3E11, IHC, WB) LS‑B11448
Note: This antibody replaces LS-C197696
Antibody:
MPO / Myeloperoxidase Mouse anti-Human Monoclonal (3E11) Antibody
Application:
IHC, IHC-P, WB, ELISA
Reactivity:
Human, Mouse
Format:
Unconjugated, Unmodified
Toll Free North America
(800) 227-6666
(800) 227-6666For Research Use Only
Overview
Antibody:
MPO / Myeloperoxidase Mouse anti-Human Monoclonal (3E11) Antibody
Application:
IHC, IHC-P, WB, ELISA
Reactivity:
Human, Mouse
Format:
Unconjugated, Unmodified
Specifications
Description
Myeloperoxidase (MPO) is a peroxidase enzyme that is highly expressed in neutrophil granulocytes. MPO produces hypohalous acids for antimicrobial processes and is the source of green coloration in pus and mucus. MPO may be a useful marker for cardiovascular diseases such as atherosclerosis, where increased concentrations of the protein have been linked to progression. In immunohistochemistry of normal tissue, it has positive cytoplasmic staining in neutrophils, Kupffer cells of the liver, and granulocytes such as eosinophils. In cancer, it is positive in myeloid leukemias and granulocytic sarcomas.
References: Journal of Leukocyte Biology. 2005 May. 77 (5): 598–625, PMID 15689384; Clin Chem. 2009 Aug;55(8):1462-70, PMID: 19556446
Target
Human MPO / Myeloperoxidase
Synonyms
MPO | Myeloperoxidase precursor | Myeloperoxidase
Host
Mouse
Reactivity
Human, Mouse
(tested or 100% immunogen sequence identity)
Clonality
IgG2b,k
Monoclonal
Clone
3E11
Conjugations
Unconjugated
Purification
Purified from ascites by Protein A
Modifications
Unmodified
Immunogen
MPO (NP_000241, aa 646-745). A partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
Specificity
Human MPO / Myeloperoxidase
Applications
- IHC
- IHC - Paraffin (10 µg/ml)
- Western blot
- ELISA
|
Performing IHC? See our complete line of Immunohistochemistry Reagents including antigen retrieval solutions, blocking agents
ABC Detection Kits and polymers, biotinylated secondary antibodies, substrates and more.
|
Usage
Sandwich ELISA: Recombinant protein. Western Blot: Cell lysate, Cell lysate, Recombinant protein.
Presentation
PBS, pH 7.4
Storage
Store at -20°C or lower. Aliquot to avoid freeze-thaw cycles.
Restrictions
For research use only. Intended for use by laboratory professionals.
About MPO / Myeloperoxidase
Validation
Anti-MPO / Myeloperoxidase antibody IHC staining of human liver. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 10 ug/ml.
Anti-MPO / Myeloperoxidase antibody IHC staining of human liver. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 10 ug/ml.
See More About...
LSBio Ratings
PathPlus™ MPO / Myeloperoxidase Antibody (clone 3E11) for IHC, WB/Western, ELISA LS-B11448 has an LSBio Rating of
Laboratory Validation Score (5)
Learn more about The LSBio Ratings Algorithm
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Featured Products
Species:
Human
Applications:
IHC, IHC - Paraffin, Western blot, ELISA
Species:
Human
Applications:
IHC, IHC - Paraffin, Western blot, ELISA
Species:
Human
Applications:
IHC, IHC - Paraffin, Western blot, Immunoprecipitation, ELISA
Species:
Mouse, Rat
Applications:
IHC, IHC - Frozen, Flow Cytometry
Request SDS/MSDS
To request an SDS/MSDS form for this product, please contact our Technical Support department at:
Technical.Support@LSBio.com
Requested From: United States
Date Requested: 11/22/2024
Date Requested: 11/22/2024
