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| Catalog Number | Size | Price |
|---|---|---|
| LS-B3727-0.05 | 0.05 mg | $460 |
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2 of 2
PathPlus™ Monoclonal Mouse anti‑Pig GFAP Antibody (clone GF‑01, IHC, WB) LS‑B3727
PathPlus™ Monoclonal Mouse anti‑Pig GFAP Antibody (clone GF‑01, IHC, WB) LS‑B3727
Note: This antibody replaces LS-C45873
Antibody:
GFAP Mouse anti-Pig Monoclonal (GF-01) Antibody
Application:
IHC, IHC-P, ICC, WB, IP
Reactivity:
Pig, Human, Feline, Porcine
Format:
Unconjugated, Unmodified
Toll Free North America
(800) 227-6666
(800) 227-6666For Research Use Only
Overview
Antibody:
GFAP Mouse anti-Pig Monoclonal (GF-01) Antibody
Application:
IHC, IHC-P, ICC, WB, IP
Reactivity:
Pig, Human, Feline, Porcine
Format:
Unconjugated, Unmodified
Specifications
Description
GFAP (glial fibrillary acidic protein) is an intermediate filament protein found in the central nervous system. Functionally, GFAP helps maintain cell shape and astrocyte mechanical strength, as well as participate in cell communication and blood brain barrier function. In immunohistochemistry, it is positive in astrocytes, ganglion cells and some ependymal cells of the central nervous system. In cancer, it is positive in ependymomas and in astrocytic tumors such as astrocytic gliomas, astrocytomas and glioblastomas.
References: Brain Research. 2007 July. 1158: 103–15. doi:10.1016/j.brainres.2007.04.070, PMID: 17555726; Neurology India. 2013. 61 (4): 383–8, PMID: 24005729; The Journal of Cell Biology. 1991 Mar. 112 (6): 1205–13. doi:10.1083/jcb.112.6.1205, PMID: 1999469; Neurosci Lett. 1996 May 3;209(1):29-32, PMID: 8734902.
Host
Mouse
Reactivity
Pig, Human, Feline, Porcine
(tested or 100% immunogen sequence identity)
Non-Reactivity
Rat
Clonality
IgG1
Monoclonal
Clone
GF-01
Conjugations
Unconjugated
Purification
Purified by protein-A affinity chromatography. Greater than 95% by SDS-PAGE.
Modifications
Unmodified
Immunogen
Pellet of porcine brain cold-stable proteins after depolymerization of microtubules
Specificity
The antibody GF-01 reacts with GFAP, the principal marker of astroglial cells in the central nervous system, which is specifically expressed in satellite cells in peripheral ganglia and in non myelinating Schwann cells in peripheral nerves. The GFAP protein runs on gels at ~55 kDa protein, usually associated with lower Mw bands which are thought to be proteolytic fragments and alternate transcripts from the single gene.
Applications
- IHC
- IHC - Paraffin (10 µg/ml)
- ICC
- Western blot
- Immunoprecipitation
|
Performing IHC? See our complete line of Immunohistochemistry Reagents including antigen retrieval solutions, blocking agents
ABC Detection Kits and polymers, biotinylated secondary antibodies, substrates and more.
|
Presentation
PBS, pH 7.4, 15 mM Sodium Azide
Storage
Store at 2°C to 8°C. Do not freeze.
Restrictions
For research use only. Intended for use by laboratory professionals.
About GFAP
Validation
Anti-GFAP antibody IHC of human brain, cortex astrocytes. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 10 ug/ml.
Anti-GFAP antibody IHC of human brain, cortex astrocytes. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 10 ug/ml.
Anti-GFAP antibody IHC of human brain, cerebellum astrocytes. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 10 ug/ml.
Anti-GFAP antibody IHC of human brain, cerebellum astrocytes. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 10 ug/ml.
See More About...
LSBio Ratings
PathPlus™ GFAP Antibody (clone GF-01) for IHC, ICC, WB/Western, IP LS-B3727 has an LSBio Rating of
Laboratory Validation Score (5)
Learn more about The LSBio Ratings Algorithm
Publications (0)
Customer Reviews (0)
Featured Products
Species:
Human, Monkey, Rat, Bat, Bovine, Horse, Rabbit
Applications:
IHC, IHC - Paraffin, Western blot, Peptide Enzyme-Linked Immunosorbent Assay
Species:
Pig, Human
Applications:
IHC, IHC - Paraffin, IHC - Frozen, Western blot, Immunoprecipitation, Flow Cytometry
Species:
Mouse, Human, Rat
Applications:
IHC, Immunofluorescence, Western blot
Species:
Human
Applications:
IHC - Paraffin, Flow Cytometry
Species:
Human
Applications:
IHC - Paraffin, Western blot, Flow Cytometry
Request SDS/MSDS
To request an SDS/MSDS form for this product, please contact our Technical Support department at:
Technical.Support@LSBio.com
Requested From: United States
Date Requested: 11/18/2024
Date Requested: 11/18/2024
