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| Catalog Number | Size | Price |
|---|---|---|
| LS-B14054-100 | 100 µl (0.5 mg/ml) | $460 |
1 of 2
2 of 2
PathPlus™ Monoclonal Mouse anti‑Human ARG1 / Arginase 1 Antibody (clone ABM4B35, aa11‑97, IHC, WB) LS‑B14054
PathPlus™ Monoclonal Mouse anti‑Human ARG1 / Arginase 1 Antibody (clone ABM4B35, aa11‑97, IHC, WB) LS‑B14054
Note: This antibody replaces LS-C358578
Antibody:
ARG1 / Arginase 1 Mouse anti-Human Monoclonal (aa11-97) (ABM4B35) Antibody
Application:
IHC, IHC-P, WB
Reactivity:
Human
Format:
Unconjugated, Unmodified
Toll Free North America
(800) 227-6666
(800) 227-6666For Research Use Only
Overview
Antibody:
ARG1 / Arginase 1 Mouse anti-Human Monoclonal (aa11-97) (ABM4B35) Antibody
Application:
IHC, IHC-P, WB
Reactivity:
Human
Format:
Unconjugated, Unmodified
Specifications
Description
Arginase 1 (ARG1) is a cytosolic enzyme that catalyzes the hydrolysis of arginine to ornithine and urea in the urea cycle. Mutations in the ARG1 gene result in impaired ureagenesis. ARG1 is expressed mainly in liver hepatocytes and to a lesser extent in subsets of bone marrow cells. It is also expressed in hepatocellular carcinoma. ARG1 antibodies are used to identify benign and malignant hepatocytes with high specificity and sensitivity and to differentiate hepatocellular carcinoma from metastatic carcinoma. Staining can also be used to identify subsets of cholangiocarcinomas.
References: Am J Surg Pathol. 2010;34(8):1147-1154. doi: 10.1097/PAS.0b013e3181e5dffa; Adv Anat Pathol. 2014;21(4):285-290. doi: 10.1097/PAP.0000000000000022; Diagn Pathol. 2012;7:149. doi: 10.1186/1746-1596-7-149; Blood. 2005;105(6):2549-2556. doi: 10.1182/blood-2004-07-2521; Oncol Lett. 2011;2(6):1041-1046. doi: 10.3892/ol.2011.405; J Mol Med (Berl). 2015;93(12):1287-1296. doi: 10.1007/s00109-015-1354-3.
Target
Human ARG1 / Arginase 1
Synonyms
ARG1 | Arginase, liver | Arginase 1 | Liver-type arginase | Liver arginase | Arginase-1 | Type I arginase
Host
Mouse
Reactivity
Human
(tested or 100% immunogen sequence identity)
Clonality
IgG2b,k
Monoclonal
Clone
ABM4B35
Conjugations
Unconjugated
Purification
Purified
Modifications
Unmodified
Immunogen
A partial length recombinant Arginase-1 protein (aa 11-97).
Epitope
aa11-97
Specificity
Human ARG1 / Arginase 1
Applications
- IHC
- IHC - Paraffin (15 µg/ml)
- Western blot
|
Performing IHC? See our complete line of Immunohistochemistry Reagents including antigen retrieval solutions, blocking agents
ABC Detection Kits and polymers, biotinylated secondary antibodies, substrates and more.
|
Presentation
PBS, 0.05% Sodium Azide
Storage
Short term: store at 4°C. Long term: aliquot and store at -20°C. Avoid freeze-thaw cycles.
Restrictions
For research use only. Intended for use by laboratory professionals.
About ARG1 / Arginase 1
Validation
Human Liver: Formalin-Fixed, Paraffin-Embedded (FFPE)
Human Liver: Formalin-Fixed, Paraffin-Embedded (FFPE)
See More About...
LSBio Ratings
PathPlus™ ARG1 / Arginase 1 Antibody (aa11-97, clone ABM4B35) for IHC, WB/Western LS-B14054 has an LSBio Rating of
Laboratory Validation Score (5)
Learn more about The LSBio Ratings Algorithm
Publications (0)
Customer Reviews (0)
Featured Products
Species:
Human
Applications:
IHC, IHC - Paraffin, Western blot, Flow Cytometry
Species:
Human, Mouse
Applications:
IHC, IHC - Paraffin, Western blot
Species:
Human
Applications:
IHC, IHC - Paraffin, Western blot, Peptide Enzyme-Linked Immunosorbent Assay
Species:
Human
Applications:
IHC, IHC - Paraffin, Western blot
Species:
Human
Applications:
IHC, IHC - Paraffin, Western blot
Request SDS/MSDS
To request an SDS/MSDS form for this product, please contact our Technical Support department at:
Technical.Support@LSBio.com
Requested From: United States
Date Requested: 11/12/2024
Date Requested: 11/12/2024
