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| Catalog Number | Size | Price |
|---|---|---|
| LS-A2035-50 | 50 µg (1 mg/ml) | $460 |
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PathPlus™ Polyclonal Rabbit anti‑Human ADGRD1 / GPR133 Antibody (Cytoplasmic Domain, IHC) LS‑A2035
PathPlus™ Polyclonal Rabbit anti‑Human ADGRD1 / GPR133 Antibody (Cytoplasmic Domain, IHC) LS‑A2035
Antibody:
ADGRD1 / GPR133 Rabbit anti-Human Polyclonal (Cytoplasmic Domain) Antibody
Application:
IHC, IHC-P
Reactivity:
Human, Monkey, Dog, Pig, Rabbit
Format:
Unconjugated, Unmodified
Overview
Antibody:
ADGRD1 / GPR133 Rabbit anti-Human Polyclonal (Cytoplasmic Domain) Antibody
Application:
IHC, IHC-P
Reactivity:
Human, Monkey, Dog, Pig, Rabbit
Format:
Unconjugated, Unmodified
Specifications
Description
ADGRD1 is an orphan adhesion G protein-coupled receptor that is transcriptionally upregulated by hypoxia in a Hif1a dependent manner. It is a critical regulator of the response to hypoxia and tumor growth in glioblastoma, and its expression levels are inversely correlated with patient survival. The receptor is widely expressed in human tissues.
References: Oncogenesis. 2016 Oct; 5(10): e263.
Target
Human ADGRD1 / GPR133
Synonyms
ADGRD1 | G protein-coupled receptor 133 | GPR133 | PGR25
Host
Rabbit
Reactivity
Human, Monkey, Dog, Pig, Rabbit
(tested or 100% immunogen sequence identity)
Predicted
Bovine, Horse (at least 90% immunogen sequence identity)
Clonality
Polyclonal
Conjugations
Unconjugated
Purification
Immunoaffinity purified
Modifications
Unmodified
Immunogen
Synthetic 19 amino acid peptide from 3rd cytoplasmic domain of human GPR133. Percent identity with other species by BLAST analysis: Human, Gorilla, Monkey, Marmoset, Dog, Panda, Rabbit, Pig (100%); Gibbon, Bovine, Elephant, Horse (95%); Mouse, Hamster (84%).
Epitope
Cytoplasmic Domain
Specificity
Human GPR133. BLAST analysis of the peptide immunogen showed no homology with other human proteins.
Applications
- IHC
- IHC - Paraffin (10 - 20 µg/ml)
|
Performing IHC? See our complete line of Immunohistochemistry Reagents including antigen retrieval solutions, blocking agents
ABC Detection Kits and polymers, biotinylated secondary antibodies, substrates and more.
|
Presentation
PBS, 0.1% Sodium Azide
Storage
Aliquot and store undiluted at -20°C or below for up to 1 year. Can be stored undiluted at 4°C for up to 1 month. Avoid freeze-thaw cycles.
Restrictions
For research use only. Intended for use by laboratory professionals.
About ADGRD1 / GPR133
Validation
Brain, Glioblastoma
Brain, Glioblastoma
Brain, Hypothalamus, PVN
Brain, Hypothalamus, PVN
Lung, non small cell carcinoma
Lung, non small cell carcinoma
Anti-GPR133 antibody IHC of human Ovary, Carcinoma. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.
Anti-GPR133 antibody IHC of human Ovary, Carcinoma. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.
Anti-GPR133 antibody IHC of human Ovary, Carcinoma. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.
Anti-GPR133 antibody IHC of human Ovary, Carcinoma. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.
Anti-GPR133 antibody IHC of human ovary, surface epithelium. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.
Anti-GPR133 antibody IHC of human ovary, surface epithelium. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.
Human Testis: Formalin-Fixed, Paraffin-Embedded (FFPE)
Human Testis: Formalin-Fixed, Paraffin-Embedded (FFPE)
Human Kidney: Formalin-Fixed, Paraffin-Embedded (FFPE)
Human Kidney: Formalin-Fixed, Paraffin-Embedded (FFPE)
See More About...
LSBio Ratings
PathPlus™ ADGRD1 / GPR133 Antibody (Cytoplasmic Domain) for IHC LS-A2035 has an LSBio Rating of
Laboratory Validation Score (5)
Learn more about The LSBio Ratings Algorithm
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Featured Products
Species:
Human
Applications:
IHC, IHC - Paraffin
Species:
Human
Applications:
IHC, IHC - Paraffin
Species:
Human
Applications:
IHC, IHC - Paraffin
Source:
E. coli
Tag:
His-GST
Request SDS/MSDS
To request an SDS/MSDS form for this product, please contact our Technical Support department at:
Technical.Support@LSBio.com
Requested From: United States
Date Requested: 11/22/2024
Date Requested: 11/22/2024
