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| Catalog Number | Size | Price |
|---|---|---|
| LS-A984-50 | 50 µg (1 mg/ml) | $460 |
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PathPlus™ Polyclonal Rabbit anti‑Human ADGRB2 / BAI2 Antibody (C‑Terminus, IHC) LS‑A984
PathPlus™ Polyclonal Rabbit anti‑Human ADGRB2 / BAI2 Antibody (C‑Terminus, IHC) LS‑A984
Antibody:
ADGRB2 / BAI2 Rabbit anti-Human Polyclonal (C-Terminus) Antibody
Application:
IHC, IHC-P
Reactivity:
Human, Monkey, Guinea pig
Format:
Unconjugated, Unmodified
Overview
Antibody:
ADGRB2 / BAI2 Rabbit anti-Human Polyclonal (C-Terminus) Antibody
Application:
IHC, IHC-P
Reactivity:
Human, Monkey, Guinea pig
Format:
Unconjugated, Unmodified
Specifications
Description
ADGRB2 (brain-specific angiogenesis inhibitor 2, BAI2) is an Orphan-B adhesion GPCR with an unknown ligand. Decreased BAI2 expression is correlated with the formation of new blood vessels in a murine ischemic model. Mutations in this gene are correlated with progressive spastic paraparesis and other neurological symptoms. Mutations affect binding to the endocytic protein endophilin A1, which is a potential interacting partner for BAI2.
References: Hum Mutat. 2017 Dec; 38(12): 1751–1760.
Host
Rabbit
Reactivity
Human, Monkey, Guinea pig
(tested or 100% immunogen sequence identity)
Predicted
Mouse, Rat, Dog, Hamster, Pig (at least 90% immunogen sequence identity)
Clonality
Polyclonal
Conjugations
Unconjugated
Purification
Immunoaffinity purified
Modifications
Unmodified
Immunogen
Synthetic 17 amino acid peptide from C-Terminus of human BAI2. Percent identity with other species by BLAST analysis: Human, Chimpanzee, Gorilla, Orangutan, Gibbon, Monkey, Galago, Marmoset, Guinea pig (100%); Mouse, Rat, Hamster, Panda, Dog, Pig (94%); Elephant, Bovine, Horse (88%); Bat, Rabbit (82%).
Epitope
C-Terminus
Specificity
Human BAI2. BLAST analysis of the peptide immunogen showed no homology with other human proteins, except PNMAL1 (53%).
Applications
- IHC
- IHC - Paraffin (10 µg/ml)
|
Performing IHC? See our complete line of Immunohistochemistry Reagents including antigen retrieval solutions, blocking agents
ABC Detection Kits and polymers, biotinylated secondary antibodies, substrates and more.
|
Presentation
PBS, 0.1% Sodium Azide
Storage
Aliquot and store undiluted at -20°C or below for up to 1 year. Can be stored undiluted at 4°C for up to 1 month. Avoid freeze-thaw cycles.
Restrictions
For research use only. Intended for use by laboratory professionals.
About ADGRB2 / BAI2
Validation
Anti-BAI2 antibody IHC of human Brain, Glioblastoma. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.
Anti-BAI2 antibody IHC of human Brain, Glioblastoma. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.
Lung, non small cell carcinoma
Lung, non small cell carcinoma
Brain, Amygdala, neurons and glia
Brain, Amygdala, neurons and glia
Anti-BAI2 antibody IHC of human Lung, Non-Small Cell Carcinoma. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.
Anti-BAI2 antibody IHC of human Lung, Non-Small Cell Carcinoma. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.
Anti-BAI2 antibody IHC of human Skin, Melanoma. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.
Anti-BAI2 antibody IHC of human Skin, Melanoma. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.
Anti-BAI2 antibody IHC of human brain, neurons. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.
Anti-BAI2 antibody IHC of human brain, neurons. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.
See More About...
LSBio Ratings
PathPlus™ ADGRB2 / BAI2 Antibody (C-Terminus) for IHC LS-A984 has an LSBio Rating of
Laboratory Validation Score (5)
Learn more about The LSBio Ratings Algorithm
Publications (0)
Customer Reviews (0)
Featured Products
Species:
Human
Applications:
IHC, IHC - Paraffin
Species:
Human, Monkey, Mouse, Rat, Dog, Hamster, Horse, Pig
Applications:
IHC, IHC - Paraffin
Species:
Human
Applications:
IHC, IHC - Paraffin
Species:
Human, Monkey, Mouse, Rat, Dog, Hamster, Horse, Pig
Applications:
IHC, IHC - Paraffin
Source:
Human
Tag:
Myc-DDK (Flag)
Request SDS/MSDS
To request an SDS/MSDS form for this product, please contact our Technical Support department at:
Technical.Support@LSBio.com
Requested From: United States
Date Requested: 11/22/2024
Date Requested: 11/22/2024
