Human TYRP1 / gp75

Mouse

Human, Mouse (tested or 100% immunogen sequence identity)

IgG2a,k Monoclonal

TA99

Unconjugated

Protein G purified

Azide-free, BSA-free. Also available Unmodified.

SK-MEL-23 cells were used as the immunogen for this TRP1 antibody.

Human RANBP2 / TRP1.

• IHC
• IHC - Frozen (0.5 - 1 µg/ml)
• Immunofluorescence (1 - 2 µg/ml)
• Flow Cytometry (0.5 - 1 µg/10E6 cells)

The applications listed have been tested for the unmodified form of this product. Other forms have not been tested. It reacts with a 75kDa melanocyte-specific gene product, identified as Tyrosinase-related protein-1 (TRP-1). It is involved in melanin synthesis. TRP1 is present on the melanosomal membranes of melanoma, normal melanocytes and nevi. Recent evidence suggests that TRP-1 is involved in maintaining stability of tyrosinase protein and modulating its catalytic activity. TRP-1 is also involved in maintenance of melanosome ultrastructure and affects melanocyte proliferation and cell death. The optimal dilution of the TRP1 antibody for each application should be determined by the researcher.

1X PBS

Store at 2°C to 8°C.

For research use only. Intended for use by laboratory professionals.

This antibody carries the LSBio 100% Guarantee.

Uniprot: P17643 NCBI: NM_000550 NP_000541.1