TRAF6

TNF receptor-associated factor 6, E3 ubiquitin protein ligase

TRAF6 is a member of the TNF receptor associated factor (TRAF) protein family. TRAF proteins are associated with, and mediate signal transduction from, members of the TNF receptor superfamily. This protein mediates signaling from members of the TNF receptor superfamily as well as the Toll/IL-1 family. Signals from receptors such as CD40, TNFSF11/RANCE and IL-1 have been shown to be mediated by this protein. This protein also interacts with various protein kinases including IRAK1/IRAK, SRC and PKCzeta, which provides a link between distinct signaling pathways. This protein functions as a signal transducer in the NF-kappaB pathway that activates IkappaB kinase (IKK) in response to proinflammatory cytokines. The interaction of this protein with UBE2N/UBC13, and UBE2V1/UEV1A, which are ubiquitin conjugating enzymes catalyzing the formation of polyubiquitin chains, has been found to be required for IKK activation by this protein. This protein also interacts with the transforming growth factor (TGF) beta receptor complex and is required for Smad-independent activation of the JNK and p38 kinases. This protein has an amino terminal RING domain which is followed by four zinc-finger motifs, a central coiled-coil region and a highly conserved carboxyl terminal domain, known as the TRAF-C domain. Two alternatively spliced transcript variants, encoding an identical protein, have been reported.

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TRAF6 (73)

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IHC-plus™ TRAF6 Antibody LS-B4867

(4.0) Rating

Antibody:

TRAF6 Rabbit anti-Human Polyclonal Antibody

Reactivity:

Human

Applications:

ICC, IF, IHC, IHC-P, WB

Format:

Unconjugated

Price:

100 µl/$485

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IHC-plus™ TRAF6 Antibody (C-Terminus) LS-B190

(4.0) Rating

Antibody:

TRAF6 Rabbit anti-Human Polyclonal (C-Terminus) Antibody

Reactivity:

Mouse, Human

Applications:

IHC, IHC-P, IP, WB

Format:

Unconjugated

Price:

50 µg/$505

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TRAF6 Antibody LS-C331172

Antibody:

TRAF6 Rabbit anti-Human Polyclonal Antibody

Reactivity:

Mouse, Rat, Human

Applications:

ICC, IF, WB

Format:

Unconjugated

Price:

20 µl/$275; 100 µl/$389

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TRAF6 Antibody (aa451-469) LS-C148303

Antibody:

TRAF6 Rabbit anti-Human Polyclonal (aa451-469) Antibody

Reactivity:

Rabbit, Mouse, Dog, Bovine, Rat, Hamster, Pig, Horse, Bat, Human

Applications:

IHC, IHC-Fr, IHC-P, IP, WB

Format:

Unconjugated

Price:

50 µl/$386

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Mouse TRAF6 (Sandwich ELISA) ELISA Kit - LS-F20213

Type:

Sandwich

Format:

96-Well Strip Plate

Reactivity:

Mouse

Range:

0.156 - 10 ng/ml

Detection:

Colorimetric - 450nm (TMB)

Sample Types:

Cell Culture Supernatants, Plasma, Serum, Tissue Homogenates

Price:

1 Plate/$783

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IHC-plus™ TRAF6 Antibody LS-B207

(4.0) Rating

Antibody:

TRAF6 Rabbit anti-Human Polyclonal Antibody

Reactivity:

Mouse, Rat, Human

Applications:

ELISA, ICC, IF, IHC, IHC-P, WB

Format:

Unconjugated

Price:

50 µg/$460

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Human TRAF6 (Sandwich ELISA) ELISA Kit - LS-F12845

Type:

Sandwich

Format:

96-Well Strip Plate

Reactivity:

Human

Range:

0.156 - 10 ng/ml

Detection:

Colorimetric - 450nm (TMB)

Sample Types:

Plasma, Serum

Price:

1 Plate/$669

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Human TRAF6 Protein (Recombinant His-SUMO) (Full Length) - LS-G21289

Source:

E. coli

Tag:

His-SUMO

Molecular Weight:

75.6 kD

Price:

100 µg/$420; 1 mg/$1,355; 20 µg/$323

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TRAF6 Antibody (clone 1B2) LS-C198368

Antibody:

TRAF6 Mouse anti-Human Monoclonal (1B2) Antibody

Reactivity:

Human

Applications:

ELISA, RNAi, WB

Format:

Unconjugated

Price:

50 µg/$423

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IHC-plus™ TRAF6 Antibody LS-B11779

(4.0) Rating

Antibody:

TRAF6 Rabbit anti-Mouse Polyclonal Antibody

Reactivity:

Mouse

Applications:

IHC, IHC-P, IP, WB

Format:

Unconjugated

Price:

50 µg/$460

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TRAF6 Antibody (aa254-475, HRP) LS-C713707

Antibody:

TRAF6 Rabbit anti-Mouse Polyclonal (aa254-475) (HRP) Antibody

Reactivity:

Mouse

Applications:

WB

Format:

HRP Conjugated

Price:

100 µl/$342; 200 µl/$388; 500 µl/$585; 1 ml/$722

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TRAF6 Antibody LS-C661213

Antibody:

TRAF6 Rabbit anti-Human Polyclonal Antibody

Reactivity:

Human

Applications:

ELISA, IF, IHC, WB

Format:

Unconjugated

Price:

100 µg/$341

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TRAF6 Antibody LS-C801460

Antibody:

TRAF6 Rabbit anti-Human Polyclonal Antibody

Reactivity:

Mouse, Rat, Human

Applications:

IF, IHC, Peptide-ELISA, WB

Format:

Unconjugated

Price:

100 µl/$379; 200 µl/$421

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TRAF6 Antibody (C-Terminus, HRP) LS-C425792

Antibody:

TRAF6 Rabbit anti-Human Polyclonal (C-Terminus) (HRP) Antibody

Reactivity:

Rabbit, Mouse, Dog, Bovine, Pig, Horse, Bat, Rat, Chimpanzee, Gibbon, Human, Monkey

Applications:

WB

Format:

HRP Conjugated

Price:

100 µl/$469

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TRAF6 Antibody (Preservative Free) LS-C815447

Antibody:

TRAF6 Rabbit anti-Human Polyclonal (Preservative Free) Antibody

Reactivity:

Human

Applications:

ICC, IF, IP, WB

Format:

Unconjugated, Preservative Free

Price:

100 µl/$412

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Human TRAF6 (Sandwich ELISA) ELISA Kit - LS-F33678

Type:

Sandwich

Format:

96-Well Strip Plate

Reactivity:

Human

Range:

0.156 - 10 ng/ml

Detection:

Colorimetric - 450nm (TMB)

Sample Types:

Plasma, Serum, Tissue Homogenates

Price:

1 Plate/$579

Select

TRAF6 Antibody LS-C830280

Antibody:

TRAF6 Rabbit anti-Human Polyclonal Antibody

Reactivity:

Mouse, Rat, Human

Applications:

ELISA, IHC, WB

Format:

Unconjugated

Price:

20 µl/$254; 60 µl/$296; 120 µl/$355; 200 µl/$450

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TRAF6 Antibody (aa153-423) LS-C296689

Antibody:

TRAF6 Rabbit anti-Human Polyclonal (aa153-423) Antibody

Reactivity:

Human

Applications:

ICC, IP, WB

Format:

Unconjugated

Price:

100 µl/$309; 200 µl/$351; 500 µl/$491; 1 ml/$561; 2 ml/$755; 5 ml/$1,225

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TRAF6 Antibody (aa153-423, PE) LS-C727775

Antibody:

TRAF6 Rabbit anti-Human Polyclonal (aa153-423) (PE) Antibody

Reactivity:

Human

Applications:

WB

Format:

PE Conjugated

Price:

100 µl/$407; 200 µl/$491; 500 µl/$850; 1 ml/$1,008; 2 ml/$1,308; 5 ml/$2,451

• Unconjugated
• PE

• Unconjugated
• PE

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TRAF6 Antibody (Internal) LS-C386496

Antibody:

TRAF6 Rabbit anti-Human Polyclonal (Internal) Antibody

Reactivity:

Mouse, Rat, Human

Applications:

ELISA, IHC, WB

Format:

Unconjugated

Price:

50 µg/$295; 100 µg/$335; 200 µg/$394

Select

TRAF6 Antibody LS-C358730

Antibody:

TRAF6 Rabbit anti-Human Polyclonal Antibody

Reactivity:

Mouse, Bovine, Rat, Human

Applications:

IHC, IP, WB

Format:

Unconjugated

Price:

50 µl/$393

Select

TRAF6 Antibody (His154) LS-C177724

Antibody:

TRAF6 Rabbit anti-Human Polyclonal (His154) Antibody

Reactivity:

Mouse, Rat, Human

Applications:

IHC, IHC-P, WB

Format:

Unconjugated

Price:

50 µl/$321; 100 µl/$403

Select

TRAF6 Antibody (aa105-154) LS-C291750

Antibody:

TRAF6 Rabbit anti-Human Polyclonal (aa105-154) Antibody

Reactivity:

Mouse, Rat, Human

Applications:

IHC, Peptide-ELISA, WB

Format:

Unconjugated

Price:

50 µl/$334; 100 µl/$397

Select

TRAF6 Antibody (Internal) LS-C413175

Antibody:

TRAF6 Rabbit anti-Human Polyclonal (Internal) Antibody

Reactivity:

Mouse, Bovine, Rat, Pig, Human

Applications:

IHC, IHC-P, WB

Format:

Unconjugated

Price:

100 µl/$321

Select

TRAF6 Antibody LS-C771358

Antibody:

TRAF6 Rabbit anti-Human Polyclonal Antibody

Reactivity:

Mouse, Rat, Human

Applications:

IF, WB

Format:

Unconjugated

Price:

60 µl/$331; 120 µl/$403; 200 µl/$529

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