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Catalog Number Size Price
LS-C187520-100 100 Tests $485 
TNFRSF12A / TWEAK Receptor Antibody - Human CD266 transfected cells stained with Mouse anti-Human CD266:RPE This image was taken for the unconjugated form of this product. Other forms have not been tested.

Monoclonal Mouse anti‑Human TNFRSF12A / TWEAK Receptor Antibody (clone ITEM‑4, RPE) LS‑C187520

Monoclonal Mouse anti‑Human TNFRSF12A / TWEAK Receptor Antibody (clone ITEM‑4, RPE) LS‑C187520

Antibody:
TNFRSF12A / TWEAK Receptor Mouse anti-Human Monoclonal (RPE) (ITEM-4) Antibody
Application:
Flo
Reactivity:
Human
Format:
R. Phycoerythrin, Unmodified
Other formats:
Price
Catalog Number
$485
LS-C187520-100
Toll Free North America
(800) 227-6666
For Research Use Only

Overview

Antibody:
TNFRSF12A / TWEAK Receptor Mouse anti-Human Monoclonal (RPE) (ITEM-4) Antibody
Application:
Flo
Reactivity:
Human
Format:
R. Phycoerythrin, Unmodified
Other formats:

Specifications

Description
TWEAK Receptor antibody LS-C187520 is an RPE-conjugated mouse monoclonal antibody to human TWEAK Receptor (TNFRSF12A). Validated for Flow.
Target
Human TNFRSF12A / TWEAK Receptor
Synonyms
TNFRSF12A | CD266 antigen | CD266 | FGF-inducible 14 | FN14 | Tweak-receptor | TWEAKR
Host
Mouse
Reactivity
Human (tested or 100% immunogen sequence identity)
Clonality
IgG2b Monoclonal
Clone
ITEM-4
Conjugations
R. Phycoerythrin. Also available Unconjugated.
Purification
Protein G purified
Modifications
Unmodified
Immunogen
Human CD266 transfected P815 cells.
Specificity
Recognizes human CD266, otherwise known as Fn14/TWEAK Receptor, a 14kD type I transmembrane glycoprotein and member of the tumor necrosis factor receptor superfamily (TNFRSF12A) expressed by a variety of tissues, including the heart, lung and kidney, and at elevated levels by human brain and liver tumors. The interaction between CD266 and its ligand CD255 (TWEAK), induces the proliferation and migration of endothelial cells and also angiogenesis, and studies have shown that CD255-induced apoptosis of some tumor cell lines is mediated by CD266, see for details. Clone ITEM-4 is cross-reactive with mouse CD266, and also with Rat-1 cells in flow cytometry.
Applications
  • Flow Cytometry
  • Applications tested for the base form of this product only
Usage
The applications listed have been tested for the unconjugated form of this product. Other forms have not been tested.
Presentation
PBS, 0.09% Sodium Azide, 5% Sucrose, 1% BSA
Reconstitution
Reconstitute with distilled water.
Storage
Store at 4°C. Do not freeze. Store undiluted. Protect from light. Microcentrifugation recommended if solution contains precipitate.
Restrictions
For research use only. Intended for use by laboratory professionals.
Guarantee
This antibody carries the LSBio 100% Guarantee.
LSBio Guarantee
About TNFRSF12A / TWEAK Receptor
Q9NP84 NM_016639 NP_057723.1

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Request SDS/MSDS

To request an SDS/MSDS form for this product, please contact our Technical Support department at:

Technical.Support@LSBio.com

Requested From: United States
Date Requested: 11/8/2024