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| Catalog Number | Size | Price |
|---|---|---|
| LS-C188542-0.2 | 0.2 mg (1 mg/ml) | $471 |
Monoclonal Mouse anti‑Human TNFRSF12A / TWEAK Receptor Antibody (clone ITEM‑4, IHC, WB) LS‑C188542
Monoclonal Mouse anti‑Human TNFRSF12A / TWEAK Receptor Antibody (clone ITEM‑4, IHC, WB) LS‑C188542
Antibody:
TNFRSF12A / TWEAK Receptor Mouse anti-Human Monoclonal (ITEM-4) Antibody
Application:
IHC, IHC-Fr, WB, Flo
Reactivity:
Human
Format:
Unconjugated, Unmodified
Other formats:
Toll Free North America
(800) 227-6666
(800) 227-6666For Research Use Only
Overview
Antibody:
TNFRSF12A / TWEAK Receptor Mouse anti-Human Monoclonal (ITEM-4) Antibody
Application:
IHC, IHC-Fr, WB, Flo
Reactivity:
Human
Format:
Unconjugated, Unmodified
Other formats:
Specifications
Description
TWEAK Receptor antibody LS-C188542 is an unconjugated mouse monoclonal antibody to human TWEAK Receptor (TNFRSF12A). Validated for Flow, IHC and WB.
Target
Human TNFRSF12A / TWEAK Receptor
Synonyms
TNFRSF12A | CD266 antigen | CD266 | FGF-inducible 14 | FN14 | Tweak-receptor | TWEAKR
Host
Mouse
Reactivity
Human
(tested or 100% immunogen sequence identity)
Clonality
IgG2b
Monoclonal
Clone
ITEM-4
Conjugations
Unconjugated.
Also available conjugated with RPE.
Purification
Protein G purified
Modifications
Unmodified
Immunogen
Human CD266 transfected P815 cells.
Specificity
Recognizes human CD266, otherwise known as Fn14/TWEAK Receptor, a 14kD type I transmembrane glycoprotein and member of the tumor necrosis factor receptor superfamily (TNFRSF12A) expressed by a variety of tissues, including the heart, lung and kidney, and at elevated levels by human brain and liver tumors. The interaction between CD266 and its ligand CD255 (TWEAK), induces the proliferation and migration of endothelial cells and also angiogenesis, and studies have shown that CD255-induced apoptosis of some tumor cell lines is mediated by CD266. Clone ITEM-4 is cross-reactive with mouse CD266, and also with Rat-1 cells in flow cytometry.
Applications
- IHC
- IHC - Frozen
- Western blot
- Flow Cytometry (1:25 - 1:200)
|
Performing IHC? See our complete line of Immunohistochemistry Reagents including antigen retrieval solutions, blocking agents
ABC Detection Kits and polymers, biotinylated secondary antibodies, substrates and more.
|
Presentation
PBS, 0.09% Sodium Azide
Storage
Store at 4°C or at -20°C. Store undiluted. Avoid freeze-thaw cycles. Microcentrifugation recommended if solution contains precipitate.
Restrictions
For research use only. Intended for use by laboratory professionals.
About TNFRSF12A / TWEAK Receptor
Publications (0)
Customer Reviews (0)
Featured Products
Species:
Human, Monkey, Mouse, Rat, Bat, Bovine, Dog, Hamster, Horse, Rabbit
Applications:
Western blot
Species:
Human
Applications:
IHC - Frozen, Western blot, Flow Cytometry
Species:
Mouse, Human, Gibbon, Monkey, Dog, Guinea pig, Pig, Rabbit
Applications:
Western blot
Reactivity:
Mouse
Range:
102-25000 pg/ml
Reactivity:
Human
Range:
125-2000 pg/ml
Reactivity:
Human
Range:
0.156-10 ng/ml
Request SDS/MSDS
To request an SDS/MSDS form for this product, please contact our Technical Support department at:
Technical.Support@LSBio.com
Requested From: United States
Date Requested: 11/8/2024
Date Requested: 11/8/2024
