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| Catalog Number | Size | Price |
|---|---|---|
| LS-B5589-50 | 50 µl (1 mg/ml) | $460 |
1 of 2
2 of 2
Polyclonal Rabbit anti‑Human SIRT6 / Sirtuin 6 Antibody (aa56‑105, IHC, WB) LS‑B5589
Polyclonal Rabbit anti‑Human SIRT6 / Sirtuin 6 Antibody (aa56‑105, IHC, WB) LS‑B5589
Note: This antibody replaces LS-C30854
Toll Free North America
(800) 227-6666
(800) 227-6666For Research Use Only
Overview
Specifications
Description
Sirtuin 6 antibody LS-B5589 is an unconjugated rabbit polyclonal antibody to Sirtuin 6 (SIRT6) (aa56-105) from human. It is reactive with human and mouse. Validated for IHC and WB. Cited in 3 publications.
Target
Human SIRT6 / Sirtuin 6
Synonyms
SIRT6 | SIR2-like protein 6 | Sirtuin type 6 | SIR2L6 | Sir2-related protein type 6 | Sirtuin 6
Host
Rabbit
Reactivity
Human, Mouse
(tested or 100% immunogen sequence identity)
Clonality
IgG
Polyclonal
Purification
Protein A purified
Modifications
Unmodified
Immunogen
Synthetic peptide located between aa56-105 of human SIRT6 (Q8N6T7, NP_057623). Percent identity by BLAST analysis: Human, Chimpanzee, Gorilla, Monkey, Galago, Marmoset, Mouse, Hamster, Elephant, Dog, Bat, Pig, Opossum (100%); Gibbon, Rat, Bovine, Horse, Guinea pig, Platypus (92%); Turkey, Zebra finch, Chicken, Xenopus (84%).
Epitope
aa56-105
Specificity
Human SIRT6
Applications
- IHC
- IHC - Paraffin (10 µg/ml)
- Western blot (1.25 µg/ml)
|
Performing IHC? See our complete line of Immunohistochemistry Reagents including antigen retrieval solutions, blocking agents
ABC Detection Kits and polymers, biotinylated secondary antibodies, substrates and more.
|
Presentation
PBS, 0.09% sodium azide, 2% sucrose
Storage
Short term: Store at 2-8°C. Long term: Aliquot and store at -20°C. Avoid freeze/thaw cycles.
Restrictions
For research use only. Intended for use by laboratory professionals.
About SIRT6 / Sirtuin 6
LSBio Ratings
SIRT6 / Sirtuin 6 Antibody (aa56-105) for IHC, WB/Western LS-B5589 has an LSBio Rating of
Publications (4.2)
Learn more about The LSBio Ratings Algorithm
Publications (3)
The RUNX2 Transcription Factor Negatively Regulates SIRT6 Expression to Alter Glucose Metabolism in Breast Cancer Cells. Choe M, Brusgard JL, Chumsri S, Bhandary L, Zhao XF, Lu S, Goloubeva OG, Polster BM, Fiskum GM, Girnun GD, Kim MS, Passaniti A. Journal of cellular biochemistry. 2015 116:2210-26. (IHC; Human)
Evaluation of the NAD+ biosynthetic pathway in ALS patients and effect of modulating NAD+ levels in hSOD1-linked ALS mouse models. Benjamin A Harlan, Kelby M Killoy, Mariana Pehar, Liping Liu, Johan Auwerx, Marcelo R Vargas. Experimental neurology. 2020 May;327:113219.
Effects of vinclozolin exposure on the expression and activity of SIRT1 and SIRT6 in the porcine ovary. G Gorczyca, K Wartalski, Z Tabarowski, M Duda. Journal of physiology and pharmacology : an official journal of the Polish Physiological Society. 2019 February;70:
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Featured Products
Species:
Human
Applications:
IHC, IHC - Paraffin, ELISA
Species:
Human, Mouse
Applications:
IHC, IHC - Paraffin, Western blot
Species:
Human
Applications:
IHC, IHC - Paraffin, Western blot
Species:
Human
Applications:
IHC, Western blot, ELISA
Species:
Human, Mouse
Applications:
IHC, IHC - Paraffin, Western blot
Reactivity:
Human
Range:
0.312-20 ng/ml
Request SDS/MSDS
To request an SDS/MSDS form for this product, please contact our Technical Support department at:
Technical.Support@LSBio.com
Requested From: United States
Date Requested: 11/7/2024
Date Requested: 11/7/2024
