Human SEMA4D / Semaphorin 4D / CD100

Mouse

Human, Monkey, Mouse (tested or 100% immunogen sequence identity)

IgG1,k Monoclonal

A8

Unconjugated

Protein G purified

Azide-free, BSA-free. Also available Unmodified.

PHA stimulated human peripheral blood lymphocytes were used as the immunogen for the Semaphorin-4D antibody.

Human SEMA4D / Semaphorin 4D / CD100

• Immunofluorescence (0.5 - 1 µg/ml)
• Flow Cytometry (0.5 - 1 µg/10E6 cells)

The applications listed have been tested for the unmodified form of this product. Other forms have not been tested. Recognizes a homodimeric protein comprised of 50kDa subunits, identified as CD100. It is expressed on majority of haemopoietic cells (B, T, NK and myeloid cells) and is absent from bone marrow, erythrocytes, eosinophils and endothelial cells. Its expression is increased after PHA-activation. CD100 was shown to associate with different partner molecules in T cells such as CD45, a key molecule with protein tyrosine phosphatase activity involved in T-cell transduction, and a Serine kinase. It plays a role in homotypic cell adhesion and in T cell activation. Optimal dilution of the Semaphorin-4D antibody to be determined by the researcher.

1X PBS

Store at 2°C to 8°C.

For research use only. Intended for use by laboratory professionals.

This antibody carries the LSBio 100% Guarantee.

Uniprot: Q92854 NCBI: NM_006378 NP_006369.3