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Vector Laboratories, Inc.
6737 Mowry Ave
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SEMA4D / Semaphorin 4D / CD100
sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4D
Cell surface receptor for PLXN1B and PLXNB2 that plays an important role in cell-cell signaling. Promotes reorganization of the actin cytoskeleton and plays a role in axonal growth cone guidance in the developing central nervous system. Regulates dendrite and axon branching and morphogenesis. Promotes the migration of cerebellar granule cells and of endothelial cells. Plays a role in the immune system; induces B-cells to aggregate and improves their viability (in vitro). Promotes signaling via SRC and PTK2B/PYK2, which then mediates activation of phosphatidylinositol 3-kinase and of the AKT1 signaling cascade. Interaction with PLXNB1 mediates activation of RHOA.
| Gene Name: | sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4D |
| Synonyms: | SEMA4D, A8, BB18, C9orf164, CD100 antigen, Coll-4, GR3, Semaphorin-4D, M-sema-G, SEMAJ, CD100 |
| Target Sequences: | NM_006378 NP_006369.3 Q92854 |
☰ Filters
Products
Antibodies
(96)
Proteins
(17)
ELISA Kits
(12)
Type
Competitive EIA
(1)
Custom
(3)
Over-Expression Lysate
(2)
Primary
(96)
Recombinant
(15)
Sandwich
(8)
Target
SEMA4D / Semaphorin 4D / CD100
(125)
Reactivity
Human
(73)
Mouse
(27)
Rat
(12)
African green monkey
(1)
Baboon
(1)
Bat
(3)
Chicken
(1)
Chimpanzee
(3)
Cynomolgus
(1)
Cynomolgus monkey
(1)
Gibbon
(3)
Guinea pig
(3)
Horse
(3)
Monkey
(6)
Pig
(3)
Rabbit
(3)
Rhesus monkey
(2)
Application
IHC
(17)
IHC-Fr
(2)
IHC-P
(1)
WB
(51)
Flo
(29)
ELISA
(24)
ICC
(1)
IF
(8)
IP
(7)
Peptide-ELISA
(3)
Host
rabbit
(57)
mouse
(38)
rat
(1)
Product Group
IHCPlus
(1)
Isotype
IgG
(16)
IgG1
(8)
IgG1,k
(8)
IgG2a
(5)
IgG2b
(4)
IgM
(8)
IgM,k
(2)
Clonality
monoclonal mc
(41)
polyclonal pc
(55)
Clone
006
(1)
06
(1)
121
(1)
133.1G6
(2)
133-1C6
(6)
1D4B
(1)
5C5B10
(1)
5H6E3
(1)
A8
(4)
OTI6G1
(4)
OTI8E6
(2)
OTI8F1
(2)
OTI8G5
(2)
SEMA4D/933
(2)
Format
12 x 8-Well Microstrips
(1)
96-Well Microplate
(2)
96-Well Strip Plate
(9)
APC
(3)
APC Conjugated
(5)
Azide-free
(4)
Biotin Conjugated
(7)
BSA-free
(3)
Carrier-free
(5)
Concentrated
(1)
Cy3 Conjugated
(3)
Cy7 Conjugated
(3)
FITC Conjugated
(8)
HRP Conjugated
(5)
PE Conjugated
(7)
Preservative Free
(4)
Unconjugated
(58)
Epitope
aa502-636
(16)
aa145-494
(8)
aa90-139
(4)
51-100 aa, N-terminal
(1)
Extracellular Domain
(1)
N-Terminus
(1)
aa24-657
(1)
aa553-587
(1)
aa793-832
(1)
aa800-850
(1)
aa812-862
(1)
Publications
No
(125)
Sample Type
Cell Culture Supernatants
(1)
Cell Lysates
(2)
Plasma
(9)
Serum
(9)
Tissue Homogenates
(5)
Tag
6His, C-terminus
(2)
Fc, C-terminus
(5)
His
(5)
His-GST-S
(1)
Myc-DDK (Flag)
(3)
Species
Human
(9)
Mouse
(4)
Rat
(3)
Source
293T Cells
(1)
CHO Cells
(1)
E. coli
(3)
HEK 293 Cells
(4)
Human Cells
(5)
Mammalian Cells
(3)
Purification
Purified
(3)
Low Endotoxin Level
Low endotoxin level
(11)
Biologically Active
Biologically active
(1)
SEMA4D / Semaphorin 4D / CD100 Mouse anti-Human Monoclonal (Biotin) (133-1C6) Antibody
Human
Flo
Biotin Conjugated
100 µg/$536
CHO Cells
None
Biologically active
Less than 0.1 ng/µg of protein (less than 1EU/µg).
78.9 kDa
5 µg/$268; 20 µg/$349
Sandwich
96-Well Strip Plate
Human
1.56 - 100 ng/ml
Colorimetric - 450nm (TMB)
Cell Lysates, Plasma, Serum, Tissue Homogenates
1 Plate/$798
Sandwich
96-Well Microplate
Human
0.31 - 20 ng/ml
Colorimetric - 450nm (TMB)
Cell Culture Supernatants, Cell Lysates, Plasma, Serum, Tissue Homogenates
1 Plate/$586
SEMA4D / Semaphorin 4D / CD100 Rabbit anti-Human Polyclonal (51-100 aa, N-terminal) Antibody
Mouse, Rat, Human
ELISA, WB
Unconjugated
50 µg/$295; 100 µg/$335; 200 µg/$394
SEMA4D / Semaphorin 4D / CD100 Rabbit anti-Human Polyclonal (aa812-862) Antibody
Human
IHC, IHC-P, IP, WB
Unconjugated
50 µl/$460
SEMA4D / Semaphorin 4D / CD100 Rabbit anti-Mouse Polyclonal Antibody
Mouse
Flo, ICC, IF
Unconjugated
100 µl/$412
SEMA4D / Semaphorin 4D / CD100 Mouse anti-Human Monoclonal (A8) Antibody
Mouse, Human, Monkey
Flo, IF
Unconjugated
20 µg/$371; 100 µg/$574
SEMA4D / Semaphorin 4D / CD100 Mouse anti-Human Monoclonal (Biotin) Antibody
Human
Flo, IHC, IHC-Fr
Biotin Conjugated
100 µg/$763
SEMA4D / Semaphorin 4D / CD100 Rabbit anti-Human Polyclonal (aa553-587) Antibody
Human
Peptide-ELISA, WB
Unconjugated
400 µl/$393
SEMA4D / Semaphorin 4D / CD100 Rabbit anti-Mouse Monoclonal (Preservative Free) (006) Antibody
Mouse
ELISA
Unconjugated, Preservative Free
20 µl/$271; 100 µl/$412
SEMA4D / Semaphorin 4D / CD100 Rabbit anti-Mouse Monoclonal (Preservative Free) (121) Antibody
Mouse
ELISA
Unconjugated, Preservative Free
20 µl/$271; 100 µl/$412
SEMA4D / Semaphorin 4D / CD100 Rabbit anti-Mouse Polyclonal (aa502-636) Antibody
Mouse
WB
Unconjugated
100 µl/$306; 200 µl/$347; 500 µl/$484; 1 ml/$553; 2 ml/$737; 5 ml/$1,206
SEMA4D / Semaphorin 4D / CD100 Mouse anti-Human Monoclonal (APC) Antibody
Human
Flo
APC Conjugated
100 Tests/$702
SEMA4D / Semaphorin 4D / CD100 Mouse anti-Human Monoclonal (5C5B10) Antibody
Human
ELISA, Flo, IHC, WB
Unconjugated
100 µl/$459
SEMA4D / Semaphorin 4D / CD100 Mouse anti-Human Monoclonal (5H6E3) Antibody
Human
ELISA, Flo, IHC, WB
Unconjugated
100 µl/$459
SEMA4D / Semaphorin 4D / CD100 Mouse anti-Human Monoclonal Antibody
Human
Flo, IHC, IHC-Fr, IP
Unconjugated
100 µg/$626
Sandwich
96-Well Strip Plate
Mouse
1.56 - 100 ng/ml
Colorimetric - 450nm (TMB)
Plasma, Serum
1 Plate/$669
E. coli
His
16.4 kDa
10 µg/$282; 50 µg/$450; 100 µg/$717; 200 µg/$897; 1 mg/$2,010; 500 µg/$1,547; 5 mg/$3,137; 2 mg/$2,198
HEK 293 Cells
His
Less than 1.0 EU/µg protein (determined by LAL method).
80.2 kDa
100 µg/$721
Sandwich
12 x 8-Well Microstrips
Mouse
0.313 - 20 ng/ml
Colorimetric - 450nm (TMB)
Plasma, Serum
1 Plate/$586
SEMA4D / Semaphorin 4D / CD100 Mouse anti-Human Monoclonal (OTI6G1) Antibody
Human
IHC, WB
Unconjugated
100 µl/$434
SEMA4D / Semaphorin 4D / CD100 Mouse anti-Human Monoclonal (OTI8F1) Antibody
Human
IHC, WB
Unconjugated
100 µl/$434
SEMA4D / Semaphorin 4D / CD100 Mouse anti-Human Monoclonal (OTI6G1) Antibody
Human
IHC, WB
Unconjugated
100 µl/$434
SEMA4D / Semaphorin 4D / CD100 Mouse anti-Human Monoclonal (OTI8E6) Antibody
Human
IHC, WB
Unconjugated
100 µl/$434
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of 125
product results
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