Human Rho Kinase / ROCK1

Mouse

Human, Monkey, Mouse, Rat, Bat, Bovine, Dog, Horse (tested or 100% immunogen sequence identity)

Rabbit (at least 90% immunogen sequence identity)

IgG Monoclonal

154C1465

Unconjugated

Protein G purified

Unmodified

This antibody was generated by immunizing mice with a synthetic peptide sequence corresponding to residues 1114-1126 GNLPESRIEGWLS of human ROCK-1. Immunogen peptide sequence is adjacent to the caspase-3 cleavage site of ROCK-1. Percent identity by BLAST analysis: Human, Chimpanzee, Gorilla, Gibbon, Monkey, Marmoset, Mouse, Rat, Elephant, Bovine, Dog, Bat, Horse, Opossum, Platypus (100%); Rabbit (92%); Chicken (85%).

aa1114-1126

This mAb recognizes the cleaved C-terminus of ROCK-1. It does not recognize the full-length protein. Since ROCK-1 is cleaved by caspase-3 during apoptosis, this may be used for detection of apoptosis.

• Western blot (1 - 2 µg/ml)

• IHC - Paraffin

PBS, 0.05% Sodium Azide, 0.2% Gelatin

Short term: store at 4°C. Long term: store at -20°C. Avoid freeze-thaw cycles.

For research use only. Intended for use by laboratory professionals.

This antibody carries the LSBio 100% Guarantee.

Uniprot: Q13464 NCBI: NM_005406 NP_005397.1