Human PP2Ac / PPP2CA

Rabbit

Human, Mouse, Rat, Bat, Bovine, Dog, Guinea pig, Pig, Rabbit, Xenopus, Zebrafish (tested or 100% immunogen sequence identity)

Horse (at least 90% immunogen sequence identity)

IgG Polyclonal

Unconjugated

Immunoaffinity purified

Unmodified

Synthetic peptide from the N-Terminus of human PPP2CA (FTKELDQWIEQLNEC, aa6-20 of UniProt P67775). Percent identity by BLAST analysis: Human, Mouse, Rat, Ferret, Cat, Bovine, Bat, Elephant, Rabbit, Pig, Opossum, Guinea pig, Lizard, Xenopus, Trout, Medaka, Salmon, Smelt, Pufferfish, Zebrafish, Stickleback, Dog (100%); Horse, Catfish (93%).

aa6-20

Human PP2Ac / PPP2CA

• IHC
• IHC - Paraffin (0.5 - 1 µg/ml)
• Western blot (0.5 - 1 µg/ml)

The catalytic subunit of human protein phosphatase 2A (PPP2CA) encodes a 309-amino acid polypeptide. It is predicted to be important for phosphatase enzymatic activity. Methylation of the C-terminal leucine residue (Leu309) of PPP2CA is known to regulate catalytic activity in vitro. Furthermore, PP2A has a fundamental role in cardiac function, and suggests that disturbances in protein phosphatase expression and activity may cause or exacerbate the course of cardiac diseases. Variations in secondary/substrate sensitivities and test protocols may require the PP2Ac antibody to be titrated for optimal performance.

Lyophilized from PBS, 2.5% BSA, 0.025% sodium azide/thimerosal.

Reconstitute in sterile distilled water.

Prior to reconstitution, 4°C. Following reconstitution store at -20°C. Avoid freeze-thaw cycles.

For research use only. Intended for use by laboratory professionals.

This antibody carries the LSBio 100% Guarantee.

Uniprot: P67775 NCBI: NM_002715 NP_002706.1