Target
Human PCSK9
Synonyms
PCSK9 | FH3 | HCHOLA3 | LDLCQ1 | NARC-1 | Proprotein convertase 9 | NARC1 | PC9
Reactivity
Human
(tested or 100% immunogen sequence identity)
Immunogen
Synthetic peptide corresponding to aa490-502 [SRSGKRRGERMEA] of human PCSK9. Species sequence Homology. Percent identity by BLAST analysis: Human, Chimpanzee, Orangutan, Gibbon (100%); Gorilla, Macaque, Monkey, Titi monkey, Woolly monkey, Colobus monkey, Tamarin (92%); Marmoset, Spider monkey, Elephant, Opossum (85%).
Specificity
Recognizes human PCSK9. Detects mainly the mature form of the protein ranging from 62-66kD in tissues and cells such as liver, kidney and colon cancer cells. Species cross-reactivity: Mouse and rat. Species sequence Homology: Mouse: ~69% (9/13aa [SRSGrRRGdwiEA]); Rat: ~77% (10/13aa [SRSGrRRGdRiEA]).