Human MYB / c-Myb

Mouse

Human (tested or 100% immunogen sequence identity)

IgG1,k Monoclonal

MYB286

Unconjugated

Protein G purified

Unmodified. Also available Azide-free, BSA-free.

Synthetic peptide (RRKVEQEGYPQESSKAG, aa119-135 of UniProt P01104) from the human protein. Percent identity by BLAST analysis: Chicken (94%); Human, Ferret, Sheep, Bovine, Pig, Turkey (88%).

aa119-135

Human MYB / c-Myb

• Flow Cytometry (0.5 - 1 µg/10E6 cells)

The highly leukemogenic avian retrovirus E26 contains two oncogenes, v-Myb and v-Ets, which are expressed together as a fusion protein. The cellular homolog of v-Myb, designated c-Myb, encodes a transcription factor. Deletion or disruption of a negative regulatory domain mapping within the carboxy-terminal domain of c-Myb results in enhanced transactivating capacity and in parallel, leads to activation of its ability to transform hemopoietic cells. c-Myb is expressed preferentially, but not exclusively, in immature hemopoietic cells and its expression decreases as cells differentiate. The optimal dilution of the c-Myb antibody for each application should be determined by the researcher.

1X PBS, 0.1 mg/ml BSA, 0.05% sodium azide

Store at 2°C to 8°C.

For research use only. Intended for use by laboratory professionals.

This antibody carries the LSBio 100% Guarantee.

Uniprot: P10242 NCBI: NM_005375 NP_005366.2