Macrophage

Rat

Mouse (tested or 100% immunogen sequence identity)

Monoclonal

MOMA-1

Unconjugated

Affinity purified

Unmodified

Lymph node

The antigen is found intracellularly and on cell surface on metallophilic macrophages. Antigen distribution: Isolated cells: No reactivity of MOMA-1 was found with dendritic cells, peritoneal resident macrophages, peritoneal exudate cells, bone marrow or blood cells. Tissue sections: Distinct macrophage subpopulations of lymphoid organs express the antigen. In the spleen, they are localized at the marginal sinus forming a ring around the periarteriolar lymphocyte sheath and follicular areas at the inner side of marginal zones. In lymph nodes, they are localized in the sinusoids and medullary cords, but not within follicular areas or paracortex. In Peyer's patches they are localized in the interfollicular areas at the serosal side. Kupffer cells in the liver can be clearly stained by MOMA-1. No MOMA- 1-positive macrophages were found in the thymus, brain, kidney, liver, skin or heart. In non-lymphoid organs, the antigen is only found on a macrophage subpopulation in the lamina propria of the villi of the small intestine. Specificity: Mouse: Subpopulation of mature resident tissue macrophages. Other: unknown

• IHC
• IHC - Frozen (1:100 - 1:200)

Lyophilized from PBS pH 7.2, 10mg/ml BSA, 0.01% thimerosal

Reconstitute with distilled water.

Store lyophilized at 4°C. Once reconstituted, aliquot and store at -20°C. Avoid freeze-thaw cycles.

For research use only. Intended for use by laboratory professionals.

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