Macrophage

Mouse

Human (tested or 100% immunogen sequence identity)

Monoclonal

25F9

FITC

Affinity purified

Unmodified

Cultured human monocytes

The antigen is a 86kDa membrane protein, the epitope has not been further characterized. Antigen distribution: Isolated cells: Absent on freshly isolated monocytes and other blood cells; present on 40 - 50% of human monocytes after 6-7 days in culture, also positive on some melanoma and carcinoma cell lines. Tissue sections: Kupffer cells, histiocytes (skin), macrophages of the thymus, in the germinal centres of lymph nodes and spleen, in mamma carcinoma, melanoma, osteocarcinoma and gastric cancer; eczema, sarcoidosis, BCG granuloma; synovial lining cells, tuberculoid leprosy: no expression in lepromatous leprosy. Specificity: Human: mature macrophages and monocytes. Other: subpopulation of macrophages in Rhesus monkey; reactive with pig alveolar macrophages and Kupffer cells.

The applications listed have been tested for the unconjugated form of this product. Other forms have not been tested.

PBS pH 7.2, 10mg/ml BSA and 0.09% sodium azide.

Store at 4°C to 8°C. Protect from light.

For research use only. Intended for use by laboratory professionals.

This antibody carries the LSBio 100% Guarantee.