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| Catalog Number | Size | Price |
|---|---|---|
| LS-C392149-20 | 20 µg (0.2 mg/ml) | $371 |
| LS-C392149-100 | 100 µg (0.2 mg/ml) | $574 |
Monoclonal Mouse anti‑Human Ku70+Ku80 / XRCC6+XRCC5 Antibody (clone LKAP1‑1) LS‑C392149
Monoclonal Mouse anti‑Human Ku70+Ku80 / XRCC6+XRCC5 Antibody (clone LKAP1‑1) LS‑C392149
Antibody:
Ku70+Ku80 / XRCC6+XRCC5 Mouse anti-Human Monoclonal (LKAP1-1) Antibody
Application:
Flo
Reactivity:
Human
Format:
Unconjugated, Unmodified
Other formats:
Toll Free North America
(800) 227-6666
(800) 227-6666For Research Use Only
Overview
Antibody:
Ku70+Ku80 / XRCC6+XRCC5 Mouse anti-Human Monoclonal (LKAP1-1) Antibody
Application:
Flo
Reactivity:
Human
Format:
Unconjugated, Unmodified
Other formats:
Specifications
Description
XRCC6+XRCC5 antibody LS-C392149 is an unconjugated mouse monoclonal antibody to human XRCC6+XRCC5 (Ku70+Ku80). Validated for Flow.
Host
Mouse
Reactivity
Human
(tested or 100% immunogen sequence identity)
Clonality
IgG1,k
Monoclonal
Clone
LKAP1-1
Conjugations
Unconjugated
Purification
Protein G purified
Modifications
Unmodified.
Also available Azide-free, BSA-free.
Immunogen
Human cell nuclear fraction.
Specificity
Human Ku70+Ku80 / XRCC6+XRCC5
Applications
- Flow Cytometry (0.5 - 1 µg/10E6 cells)
Usage
Together, Ku70 and Ku80 make up the Ku heterodimer, which binds to DNA double-strand break ends and is required for the non-homologous end joining (NHEJ) pathway of DNA repair. It is also required for V (D)J recombination, which utilizes the NHEJ pathway to promote antigen diversity in the mammalian immune system. In addition to its role in NHEJ, Ku is also required for telomere length maintenance and subtelomeric gene silencing. Ku was originally identified when patients with systemic lupus erythematosus were found to have high levels of autoantibodies to the protein. Titering of the Ku70 + Ku80 antibody may be required for optimal performance.
Presentation
1X PBS, 0.1 mg/ml BSA, 0.05% sodium azide
Storage
Store at 2°C to 8°C.
Restrictions
For research use only. Intended for use by laboratory professionals.
Publications (0)
Customer Reviews (0)
Featured Products
Species:
Human
Applications:
IHC, IHC - Paraffin, Immunofluorescence, Western blot, Peptide Enzyme-Linked Immunosorbent Assay
Species:
Human, Primate
Applications:
IHC, IHC - Paraffin, ICC, Immunofluorescence, Immunoprecipitation, Flow Cytometry
Species:
Human, Mouse, Rat
Applications:
IHC, Immunofluorescence, Western blot
Species:
Human, Mouse, Rat
Applications:
IHC, Immunofluorescence, Western blot, ELISA
Species:
Human, Primate
Applications:
IHC, IHC - Paraffin, ICC, Immunofluorescence, Immunoprecipitation, Flow Cytometry
Source:
Insect
Tag:
His,N-terminus
Request SDS/MSDS
To request an SDS/MSDS form for this product, please contact our Technical Support department at:
Technical.Support@LSBio.com
Requested From: United States
Date Requested: 11/12/2024
Date Requested: 11/12/2024
