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| Catalog Number | Size | Price |
|---|---|---|
| LS-C392151-100 | 100 µg (1 mg/ml) | $574 |
Monoclonal Mouse anti‑Human Ku70+Ku80 / XRCC6+XRCC5 Antibody (clone LKAP1‑1, Azide‑free,BSA‑free) LS‑C392151
Monoclonal Mouse anti‑Human Ku70+Ku80 / XRCC6+XRCC5 Antibody (clone LKAP1‑1, Azide‑free,BSA‑free) LS‑C392151
Antibody:
Ku70+Ku80 / XRCC6+XRCC5 Mouse anti-Human Monoclonal (Azide-free, BSA-free) (LKAP1-1) Antibody
Application:
Flo
Reactivity:
Human
Format:
Unconjugated, Azide-free, BSA-free
Other formats:
Toll Free North America
(800) 227-6666
(800) 227-6666For Research Use Only
Overview
Antibody:
Ku70+Ku80 / XRCC6+XRCC5 Mouse anti-Human Monoclonal (Azide-free, BSA-free) (LKAP1-1) Antibody
Application:
Flo
Reactivity:
Human
Format:
Unconjugated, Azide-free, BSA-free
Other formats:
Specifications
Description
XRCC6+XRCC5 antibody LS-C392151 is an unconjugated mouse monoclonal antibody to human XRCC6+XRCC5 (Ku70+Ku80). Validated for Flow.
Host
Mouse
Reactivity
Human
(tested or 100% immunogen sequence identity)
Clonality
IgG1,k
Monoclonal
Clone
LKAP1-1
Conjugations
Unconjugated
Purification
Protein G purified
Modifications
Azide-free, BSA-free.
Also available Unmodified.
Immunogen
Human cell nuclear fraction.
Specificity
Human Ku70+Ku80 / XRCC6+XRCC5
Applications
- Flow Cytometry (0.5 - 1 µg/10E6 cells)
Usage
The applications listed have been tested for the unmodified form of this product. Other forms have not been tested. Together, Ku70 and Ku80 make up the Ku heterodimer, which binds to DNA double-strand break ends and is required for the non-homologous end joining (NHEJ) pathway of DNA repair. It is also required for V (D)J recombination, which utilizes the NHEJ pathway to promote antigen diversity in the mammalian immune system. In addition to its role in NHEJ, Ku is also required for telomere length maintenance and subtelomeric gene silencing. Ku was originally identified when patients with systemic lupus erythematosus were found to have high levels of autoantibodies to the protein. Titering of the Ku70 + Ku80 antibody may be required for optimal performance.
Presentation
1X PBS
Storage
Store at 2°C to 8°C.
Restrictions
For research use only. Intended for use by laboratory professionals.
Publications (0)
Customer Reviews (0)
Featured Products
Species:
Human, Primate
Applications:
IHC, IHC - Paraffin, ICC, Immunofluorescence, Immunoprecipitation, Flow Cytometry
Species:
Human
Applications:
IHC, IHC - Paraffin, Immunofluorescence, Western blot, Peptide Enzyme-Linked Immunosorbent Assay
Species:
Human, Mouse, Rat
Applications:
IHC, Immunofluorescence, Western blot
Species:
Human, Mouse, Rat
Applications:
IHC, Immunofluorescence, Western blot, ELISA
Species:
Human, Primate
Applications:
IHC, IHC - Paraffin, ICC, Immunofluorescence, Immunoprecipitation, Flow Cytometry
Source:
Insect
Tag:
His,N-terminus
Request SDS/MSDS
To request an SDS/MSDS form for this product, please contact our Technical Support department at:
Technical.Support@LSBio.com
Requested From: United States
Date Requested: 3/15/2025
Date Requested: 3/15/2025
