Human KRT16 / CK16 / Cytokeratin 16

Mouse

Human (tested or 100% immunogen sequence identity)

IgG1 Monoclonal

LL025

Unconjugated

Purified

Unmodified

Synthetic peptide corresponding to an amino acid sequence of the C-Terminus of human keratin 16

reacts against keratin 16, which is specifically found in hyperproliferative squamous epithelium such as psoriatic lesions and squamous cell carcinomas, e.g. of the lung. It is expressed in suprabasal keratinocytes of wounded epidermis, a situation of high cell turnover. Reactivity is negative in, e.g. normal skin, breast and lung tissue and non-invasive breast carcinoma. However, 10% of the invasive breast carcinomas tested were diffusely or focally positive with this antibody.

• IHC
• IHC - Frozen (1:25 - 1:50)
• Western blot

• IHC - Paraffin

For immunohistochemistry on paraffin embedded tissue sections, high pressure retreival at pH 8.0 is recommended.

PBS, 0.09% Sodium Azide

Short term: store at 4°C. Long term: aliquot and store at -20°C. Avoid freeze-thaw cycles. Store undiluted.

For research use only. Intended for use by laboratory professionals.

This antibody carries the LSBio 100% Guarantee.

Uniprot: P08779 NCBI: NM_005557 NP_005548.2