Target
Rat KLRB1 / CD161
Synonyms
KLRB1 | CD161 antigen | CLEC5B | CD161 | NKR-P1A | NKR | HNKR-P1A | NKR-P1 | NKRP1A
Reactivity
Rat
(tested or 100% immunogen sequence identity)
Clonality
IgG1
Monoclonal
Conjugations
R. Phycoerythrin.
Also available
Unconjugated or conjugated with
FITC.
Purification
Protein G purified
Immunogen
Purified splenic NK cells from the LEW rat strain.
Specificity
Recognizes the rat Killer cell lectin-like receptor subfamily B protein, also known as NKR-PI or CD161. CD161 is a 233 amino acid ~60 kD type II single pass protein containing a single domain. CD161 is expressed on rat NK cells and T cell subpopulations. CD161 exists in 2 forms NKR-PIa and NKR-PIb, clone 10/78 Ârecognizes both forms of CD161. Clone 10/78 competes with another anti CD161 clone, 3.2.3 for binding to antigen. Has been successfully employed for the in vivo depletion of rat NK cells in an experimental obesity model.
Applications
- Flow Cytometry (1:1 - 1:10)
- Applications tested for the base form of this product only
Usage
The applications listed have been tested for the unconjugated form of this product. Other forms have not been tested. Flow Cytometry: Use 10 ul of the suggested working dilution to label 10^6 cells in 100 ul. Method sheets are available on request.
Presentation
PBS, 0.09% Sodium Azide, 5% Sucrose, 1% BSA
Reconstitution
Reconstitute with distilled water.
Storage
Store at 4°C. Do not freeze. Store undiluted. Protect from light. Microcentrifugation recommended if solution contains precipitate.
Restrictions
For research use only. Intended for use by laboratory professionals.
Guarantee
This antibody carries the LSBio 100% Guarantee.
LSBio Guarantee