Login
Registration enables users to use special features of this website, such as past
order histories, retained contact details for faster checkout, review submissions, and special promotions.
order histories, retained contact details for faster checkout, review submissions, and special promotions.
Forgot password?
Registration enables users to use special features of this website, such as past
order histories, retained contact details for faster checkout, review submissions, and special promotions.
order histories, retained contact details for faster checkout, review submissions, and special promotions.
Quick Order
Products
Antibodies
ELISA and Assay Kits
Research Areas
Infectious Disease
Resources
Purchasing
Reference Material
Contact Us
Location
Corporate Headquarters
Vector Laboratories, Inc.
6737 Mowry Ave
Newark, CA 94560
United States
Telephone Numbers
Customer Service: (800) 227-6666 / (650) 697-3600
Contact Us
Additional Contact Details
Login
Registration enables users to use special features of this website, such as past
order histories, retained contact details for faster checkout, review submissions, and special promotions.
order histories, retained contact details for faster checkout, review submissions, and special promotions.
Forgot password?
Registration enables users to use special features of this website, such as past
order histories, retained contact details for faster checkout, review submissions, and special promotions.
order histories, retained contact details for faster checkout, review submissions, and special promotions.
Quick Order
KLRB1 / CD161
killer cell lectin-like receptor subfamily B, member 1
Plays an inhibitory role on natural killer (NK) cells cytotoxicity. Activation results in specific acid sphingomyelinase/SMPD1 stimulation with subsequent marked elevation of intracellular ceramide. Activation also leads to AKT1/PKB and RPS6KA1/RSK1 kinases stimulation as well as markedly enhanced T-cell proliferation induced by anti-CD3. Acts as a lectin that binds to the terminal carbohydrate Gal-alpha(1,3)Gal epitope as well as to the N-acetyllactosamine epitope. Binds also to CLEC2D/LLT1 as a ligand and inhibits NK cell-mediated cytotoxicity as well as interferon-gamma secretion in target cells.
| Gene Name: | killer cell lectin-like receptor subfamily B, member 1 |
| Synonyms: | KLRB1, CD161 antigen, CLEC5B, CD161, NKR-P1A, NKR, HNKR-P1A, NKR-P1, NKRP1A |
| Target Sequences: | NM_002258 NP_002249.1 Q12918 |
Publications (2)
1
IL-12, IL-15, and IL-18 pre-activated NK cells target resistant T cell acute lymphoblastic leukemia and delay leukemia development in vivo. Boieri M, Ulvmoen A, Sudworth A, Lendrem C, Collin M, Dickinson AM, Kveberg L, Inngjerdingen M. Oncoimmunology. 2017 January;6:e1274478. (Human)
[Full Text Article]
[PubMed:28405496]
[PMC:PMC5384344]
Related Antibodies: LS-C35855.
2
Immunohistochemical Evidence of the Involvement of Natural Killer (CD161+) Cells in Spontaneous Regression of Lewis Rat Sarcoma. Jana Kovalska, Monika Cervinkova, Eva Chmelikova, Daniela Planska, Jana Cizkova, Vratislav Horak. In Vivo. 2018 December;33:47-52. [Full Text Article]
[PubMed:30587601]
[PMC:PMC6364084]
☰ Filters
Products
Antibodies
(61)
Type
Primary
(61)
Target
KLRB1 / CD161
(61)
Reactivity
Human
(49)
Mouse
(3)
Rat
(13)
Non-Human Primates
(2)
Pig
(8)
Application
IHC
(12)
IHC-Fr
(8)
WB
(27)
Flo
(39)
ELISA
(6)
IP
(14)
RIA
(4)
Host
rabbit
(14)
mouse
(47)
Isotype
IgG
(5)
IgG1
(26)
IgG1,k
(11)
IgG2b
(8)
IgG2b,k
(2)
Clonality
monoclonal mc
(47)
polyclonal pc
(14)
Clone
10/78
(7)
14F1F11
(1)
14F2F11
(1)
2F3
(1)
4C6A11
(1)
B199.2
(11)
HP-3G10
(13)
OTI1D8
(2)
OTI5F10
(2)
Format
AF488 Conjugated
(1)
AF647 Conjugated
(1)
APC
(1)
APC Conjugated
(2)
Biotin Conjugated
(5)
Carrier-free
(2)
Cy3 Conjugated
(1)
Cy5 Conjugated
(1)
Cy5.5
(1)
Cy5.5 Conjugated
(1)
Cy7 Conjugated
(2)
FITC Conjugated
(8)
HRP Conjugated
(3)
PE
(3)
PE Conjugated
(7)
PerCP Conjugated
(1)
Preservative Free
(2)
RPE Conjugated
(2)
Unconjugated
(26)
Epitope
aa73-188
(8)
aa67-225
(4)
aa68-225
(2)
101-150 aa, Internal
(1)
Publications
No
(60)
Yes
(1)
KLRB1 / CD161 Mouse anti-Human Monoclonal (Biotin) (B199.2) Antibody
Human
Flo
Biotin Conjugated
100 µg/$626
KLRB1 / CD161 Mouse anti-Human Monoclonal (B199.2) Antibody
Human
Flo, IHC, IHC-Fr, IP
Unconjugated
100 µg/$562; 200 µg/$755
KLRB1 / CD161 Mouse anti-Human Monoclonal (Biotin) Antibody
Human
Flo, IHC, IP
Biotin Conjugated
100 µl/$836
KLRB1 / CD161 Mouse anti-Human Monoclonal (FITC) Antibody
Human
Flo, IHC, IP
FITC Conjugated
100 µl/$836
KLRB1 / CD161 Mouse anti-Rat Monoclonal Antibody
Rat
Flo, IHC, IHC-Fr, IP
Unconjugated
100 µg/$572; 250 µg/$771
KLRB1 / CD161 Mouse anti-Rat Monoclonal (HRP) Antibody
Rat
Flo, IHC, IP
HRP Conjugated
100 µl/$848
KLRB1 / CD161 Mouse anti-Rat Monoclonal (Biotin) Antibody
Rat
Flo, IHC, IP
Biotin Conjugated
100 µl/$848
KLRB1 / CD161 Mouse anti-Rat Monoclonal (PE) Antibody
Rat
Flo, IHC, IP
PE Conjugated
100 Tests/$794
KLRB1 / CD161 Mouse anti-Rat Monoclonal (10/78) Antibody
Rat
Flo, IHC, IHC-Fr, IP
Unconjugated
0.1 mg/$395
KLRB1 / CD161 Mouse anti-Human Monoclonal (aa67-225) (OTI1D8) Antibody
Human
IHC, WB
Unconjugated
100 µl/$434
KLRB1 / CD161 Mouse anti-Human Monoclonal (aa67-225) (Carrier-free) (OTI1D8) Antibody
Human
IHC, WB
Unconjugated, Carrier-free
100 µg/$511
KLRB1 / CD161 Mouse anti-Rat Monoclonal (Preservative Free) (10/78) Antibody
Rat
Flo, IHC-Fr, IP, RIA, WB
Unconjugated, Preservative Free
1 mg/$712
KLRB1 / CD161 Mouse anti-Human Monoclonal (B199.2) Antibody
Human
Flo, IHC-Fr, IP
Unconjugated
0.1 mg/$385
KLRB1 / CD161 Mouse anti-Human Monoclonal (aa68-225) (14F1F11) Antibody
Human
WB
Unconjugated
0.1 mg/$386
KLRB1 / CD161 Rabbit anti-Human Polyclonal Antibody
Mouse, Rat, Human
WB
Unconjugated
20 µl/$275; 100 µl/$389
KLRB1 / CD161 Mouse anti-Human Monoclonal (4C6A11) Antibody
Human
ELISA, Flo, WB
Unconjugated
100 µl/$459
KLRB1 / CD161 Mouse anti-Rat Monoclonal (10/78) Antibody
Rat
Flo, IHC-Fr, IP, RIA, WB
Unconjugated
0.1 mg/$281
KLRB1 / CD161 Mouse anti-Rat Monoclonal (FITC) (10/78) Antibody
Rat
Flo, IHC-Fr, IP, RIA, WB
FITC Conjugated
0.1 mg/$323
KLRB1 / CD161 Mouse anti-Rat Monoclonal (PE) (10/78) Antibody
Rat
Flo, IHC-Fr, IP, RIA, WB
PE Conjugated
0.1 mg/$337
KLRB1 / CD161 Rabbit anti-Human Polyclonal Antibody
Human
ELISA, IHC, WB
Unconjugated
20 µl/$254; 60 µl/$296; 120 µl/$355; 200 µl/$450
KLRB1 / CD161 Mouse anti-Human Monoclonal (HP-3G10) Antibody
Human, Non-Human Primates
Flo, WB
Unconjugated
0.1 mg/$302
KLRB1 / CD161 Mouse anti-Human Monoclonal (PE) (HP-3G10) Antibody
Human, Non-Human Primates
Flo, WB
PE Conjugated
100 Tests/$365
KLRB1 / CD161 Mouse anti-Human Monoclonal (2F3) Antibody
Human
ELISA, WB
Unconjugated
100 µg/$423
KLRB1 / CD161 Rabbit anti-Human Polyclonal (101-150 aa, Internal) Antibody
Human
ELISA, WB
Unconjugated
50 µg/$295; 100 µg/$335; 200 µg/$394
KLRB1 / CD161 Rabbit anti-Human Polyclonal Antibody
Human
ELISA, WB
Unconjugated
50 µl/$334; 100 µl/$397
Viewing 1-25
of 61
product results
If you do not find the reagent or information you require, please contact Customer.Support@LSBio.com to inquire about additional products in development.
