Target
Human KCNJ3 / GIRK1
Synonyms
KCNJ3 | GIRK1 | Kcnf3 | KIR3.1 | GIRK-1 | HGIRK1 | KGA
Reactivity
Human
(tested or 100% immunogen sequence identity)
Conjugations
Horseradish Peroxidase.
Also available
Unconjugated or conjugated with
Biotin,
FITC.
Immunogen
Recombinant Human G protein-activated inward rectifier potassium channel 1 protein (350-487AA)
Specificity
This potassium channel is controlled by G proteins. Inward rectifier potassium channels are characterized by a greater tendency to allow potassium to flow into the cell rather than out of it. Their voltage dependence is regulated by the concentration of extracellular potassium; as external potassium is raised, the voltage range of the channel opening shifts to more positive voltages. The inward rectification is mainly due to the blockage of outward current by internal magnesium. This receptor plays a crucial role in regulating the heartbeat.