Mouse ITGB1 / Integrin Beta 1 / CD29

Hamster

Mouse (tested or 100% immunogen sequence identity)

IgG Monoclonal

HM beta 1-1

R. Phycoerythrin. Also available Unconjugated or conjugated with FITC.

Protein G purified

Unmodified

Purified mouse VLA-4 antigen.

Recognizes the murine integrin beta 1 subunit (CD29), a 110KD cell surface glycoprotein that is widely expressed by a variety of cells including all leucocytes. CD29 forms non-covalent bonds with the integrin alpha subunits, including CD51 and CD49a-f, to form heterodimers. The ligands for these heterodimers include collagen, fibronectin, laminin and vascular adhesion molecule-1. In the immune system beta 1 integrins play an important role in cell adhesion, migration, activation and differentiation. Clone HM beta 1.1 is reported to inhibit beta 1 integrin mediated adhesion. XXX recommend the use of MCA2298EL for this purpose.

• Flow Cytometry (1:1 - 1:5)
• Applications tested for the base form of this product only

The applications listed have been tested for the unconjugated form of this product. Other forms have not been tested. Flow Cytometry: Use 10 ul of the suggested working dilution to label 10^6 cells in 100 ul. The Fc region of monoclonal antibodies may bind non-specifically to cells expressing low affinity Fc receptors.

PBS, 0.09% Sodium Azide, 5% Sucrose, 1% BSA

Reconstitute with distilled water.

Store at 4°C. Do not freeze. Store untiluted. Protect from light.

For research use only. Intended for use by laboratory professionals.

This antibody carries the LSBio 100% Guarantee.

Uniprot: P05556 NCBI: NM_002211 NP_002202.2