Mouse ITGB1 / Integrin Beta 1 / CD29

Hamster

Mouse (tested or 100% immunogen sequence identity)

IgG Monoclonal

HM beta 1-1

FITC. Also available Unconjugated or conjugated with RPE.

Protein G purified

Unmodified

Purified mouse VLA-4 antigen.

Recognizes the murine integrin beta 1 subunit (CD29), a 110KD cell surface glycoprotein that is widely expressed by a variety of cells including all leucocytes. CD29 forms non-covalent bonds with the integrin alpha subunits, including CD51 and CD49a-f, to form heterodimers. The ligands for these heterodimers include collagen, fibronectin, laminin and vascular adhesion molecule-1. In the immune system beta 1 integrins play an important role in cell adhesion, migration, activation and differentiation. Clone HM beta 1.1 is reported to inhibit beta 1 integrin mediated adhesion. XXX recommend the use of MCA2298EL for this purpose.

• Flow Cytometry (1:1 - 1:10)
• Applications tested for the base form of this product only

• IHC - Paraffin

The applications listed have been tested for the unconjugated form of this product. Other forms have not been tested. Flow Cytometry: Use 10 ul of the suggested working dilution to label 10^6 cells in 100 ul. The Fc region of monoclonal antibodies may bind non-specifically to cells expressing low affinity Fc receptors.

PBS, 0.09% Sodium Azide, 1% BSA

Store at 4°C or at -20°C. Store undiluted. Avoid freeze-thaw cycles. Protect from light.

For research use only. Intended for use by laboratory professionals.

This antibody carries the LSBio 100% Guarantee.

Uniprot: P05556 NCBI: NM_002211 NP_002202.2