Human ITGAM / CD11b

Mouse

Human (tested or 100% immunogen sequence identity)

IgG1 Monoclonal

X-5

Unconjugated

Affinity purified

Unmodified

Human monocytes

The antigen is CD11b, the epitope has not been further characterized. Antigen distribution: Isolated cells: Weakly positive on granulocytes, positive on peritoneal macrophages, negative on lymphocytes. Positive on HL-60 cells , particularly after DMSO treatment. Tissue sections: In lymph nodes, monoclonal antibody X-5 is positive on monocytes, macrophages and single cells both intrafollicularly and in surrounding blood vessels. Positive staining has been observed with the basal membrane of blood vessels and on sinus walls. Marginal zone macrophages, medulla and red pulp stain positive in the spleen as do cells in the T-cell region. In the thymus, medulla and trabecular macrophages are positive. Specificity: Human: granulocytes, monocytes, (NK- cells). Other: not tested.

• IHC
• IHC - Frozen (1:100 - 1:200)

Lyophilized from PBS, pH 7.2, 5 mg/ml BSA, 0.09% Sodium Azide

Reconstitute with distilled water.

Store lyophilized product at 4°C. Aliquot and store at -20°C after reconstitution. Avoid freeze-thaw cycles. Stable for 1 year.

For research use only. Intended for use by laboratory professionals.

This antibody carries the LSBio 100% Guarantee.

Uniprot: P11215 NCBI: NM_000632 NP_000623.2